BDNF Protein (AA 1-247) (His tag)
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- Target See all BDNF Proteins
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-247
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BDNF protein is labelled with His tag.
- Sequence
- Met1-Arg247
- Characteristics
- A DNA sequence encoding theHuman BDNF protein (P23560) (Met1-Arg247) was expressed with a C-His.
- Purity
- >85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BDNF Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Alternative Name
- BDNF (BDNF Products)
- Synonyms
- ANON2 Protein, BULN2 Protein, bdnf-A Protein, BDNF Protein, bdnf Protein, brain derived neurotrophic factor Protein, brain-derived neurotrophic factor Protein, brain-derived neurotrophic factor L homeolog Protein, brain-derived neurotrophic factor S homeolog Protein, BDNF Protein, Bdnf Protein, bdnf Protein, bdnf.L Protein, bdnf.S Protein
- Background
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Background: Important signaling molecule that activates signaling cascades downstream of NTRK2.During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Synonym: Abrineurin,ProBDNF
- Molecular Weight
- 26 kDa
- UniProt
- P23560
- Pathways
- RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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