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BDNF Protein (AA 1-247) (His tag)

BDNF Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505610
  • Target See all BDNF Proteins
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-247
    Origin
    • 23
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 34
    • 17
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This BDNF protein is labelled with His tag.
    Sequence
    Met1-Arg247
    Characteristics
    A DNA sequence encoding theHuman BDNF protein (P23560) (Met1-Arg247) was expressed with a C-His.
    Purity
    >85 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product BDNF Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    Alternative Name
    BDNF (BDNF Products)
    Synonyms
    ANON2 Protein, BULN2 Protein, bdnf-A Protein, BDNF Protein, bdnf Protein, brain derived neurotrophic factor Protein, brain-derived neurotrophic factor Protein, brain-derived neurotrophic factor L homeolog Protein, brain-derived neurotrophic factor S homeolog Protein, BDNF Protein, Bdnf Protein, bdnf Protein, bdnf.L Protein, bdnf.S Protein
    Background

    Background: Important signaling molecule that activates signaling cascades downstream of NTRK2.During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

    Synonym: Abrineurin,ProBDNF

    Molecular Weight
    26 kDa
    UniProt
    P23560
    Pathways
    RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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