IL6RA Protein (AA 1-365) (His tag)

Catalog No. ABIN7505654

Product Details

Target: IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Protein Type: Recombinant

Protein Characteristics: AA 1-365

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This IL6RA protein is labelled with His tag.

Sequence: Met1-Pro365

Characteristics: A DNA sequence encoding the Human IL-6R protein (P08887) (Met1-Pro365) was expressed with a C-His.

Purity: >95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Alternative Name: IL6RA (IL6RA Products)

Synonyms: IL6R1 Protein, Il6ra Protein, CD126 Protein, IL-6R-1 Protein, IL-6RA Protein, IL6Q Protein, IL6RA Protein, IL6RQ Protein, gp80 Protein, IL-6R Protein, Il6r Protein, interleukin 6 receptor Protein, interleukin 6 receptor, alpha Protein, Il6r Protein, IL6R Protein, Il6ra Protein

Background:

Background: Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (sIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both

Synonym: Interleukin-6 receptor subunit alpha,IL-6R subunit alpha,IL-6R-alpha,IL-6R 1,Membrane glycoprotein 80,gp80,CD126,IL-6R,IL-6R-1,IL-6RA,IL6Q,IL6RQ

Molecular Weight: 40.04 kDa

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints