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Biglycan Protein (BGN) (His tag)

BGN Origin: Human Host: HEK-293 Cells Recombinant > 80 % by SDS-PAGE.
Catalog No. ABIN7519707
  • Target See all Biglycan (BGN) Proteins
    Biglycan (BGN)
    Protein Type
    Recombinant
    Origin
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Biglycan protein is labelled with His tag.
    Purpose
    Recombinant Human Biglycan/BGN Protein
    Sequence
    DEEASGADTS GVLDPDSVTP TYSAMCPFGC HCHLRVVQCS DLGLKSVPKE ISPDTTLLDL QNNDISELRK DDFKGLQHLY ALVLVNNKIS KIHEKAFSPL RKLQKLYISK NHLVEIPPNL PSSLVELRIH DNRIRKVPKG VFSGLRNMNC IEMGGNPLEN SGFEPGAFDG LKLNYLRISE AKLTGIPKDL PETLNELHLD HNKIQAIELE DLLRYSKLYR LGLGHNQIRM IENGSLSFLP TLRELHLDNN KLARVPSGLP DLKLLQVVYL HSNNITKVGV NDFCPMGFGV KRAYYNGISL FNNPVPYWEV QPATFRCVTD RLAIQFGNYK K
    Specificity
    Asp38-Lys368
    Purity
    > 80 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product BGN Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    Biglycan (BGN)
    Alternative Name
    Biglycan/BGN (BGN Products)
    Synonyms
    DSPG1 Protein, PG-S1 Protein, PGI Protein, SLRR1A Protein, BG Protein, BSPG1 Protein, bgn Protein, zgc:91989 Protein, dspg1 Protein, pg-s1 Protein, slrr1a Protein, xbgn Protein, BGN Protein, zgc:77123 Protein, DKFZp468I2427 Protein, biglycan Protein, biglycan L homeolog Protein, biglycan a Protein, biglycan S homeolog Protein, biglycan b Protein, BGN Protein, Bgn Protein, bgn.L Protein, bgna Protein, bgn.S Protein, bgn Protein, bgnb Protein
    Background

    Description: Biglycan, also known as PG I, is a secreted chondroitin/dermatan sulfate proteoglycan in the small leucine-rich proteoglycan (SLRP) family.The protein is plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, It may contribute to atherosclerosis and aortic valve stenosis in human patients.

    Name: BGN,DSPG1,MRLS,PG-S1,PGI,SEMDX,SLRR1A,biglycan

    Gene ID
    633
    UniProt
    P21810
    Pathways
    Glycosaminoglycan Metabolic Process
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