CD69 Protein (CD69) (His tag)
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- Target See all CD69 Proteins
- CD69
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD69 protein is labelled with His tag.
- Purpose
- Recombinant Human CD69 Protein
- Sequence
- SVGQYNCPGQ YTFSMPSDSH VSSCSEDWVG YQRKCYFIST VKRSWTSAQN ACSEHGATLA VIDSEKDMNF LKRYAGREEH WVGLKKEPGH PWKWSNGKEF NNWFNVTGSD KCVFLKNTEV SSMECEKNLY WICNKPYK
- Specificity
- Ser62-Lys199
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Top Product
- Discover our top product CD69 Protein
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CD69 (CD69) (AA 62-199) protein (His tag)
CD69 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD69 (CD69) (AA 62-199) protein (His tag)CD69 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD69 (CD69) (AA 1-199) protein (GST tag)CD69 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD69 (CD69) (AA 90-199) protein (GST tag)CD69 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD69 (CD69) protein (His tag,ECD)CD69 Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
CD69 (CD69) protein (Fc Tag,ECD)CD69 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- CD69
- Alternative Name
- CD69 (CD69 Products)
- Synonyms
- 5830438K24Rik Protein, AI452015 Protein, AIM Protein, VEA Protein, BL-AC/P26 Protein, CLEC2C Protein, EA1 Protein, GP32/28 Protein, MLR-3 Protein, Cd69 molecule Protein, CD69 antigen Protein, CD69 molecule Protein, Cd69 Protein, CD69 Protein
- Background
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Description: Early activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients.
Name: CD69,AIM,BL-AC/P26,CLEC2C,EA1,GP32/28,MLR-3
- Gene ID
- 969
- UniProt
- Q07108
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