IL-10RA Protein (Fc Tag)

Catalog No. ABIN7536111

Product Details

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This IL-10RA protein is labelled with Fc Tag.

Purpose: Active Recombinant Human IL-10 R alpha/IL10RA/CD210 Protein

Sequence: HGTELPSPPS VWFEAEFFHH ILHWTPIPNQ SESTCYEVAL LRYGIESWNS ISNCSQTLSY DLTAVTLDLY HSNGYRARVR AVDGSRHSNW TVTNTRFSVD EVTLTVGSVN LEIHNGFILG KIQLPRPKMA PANDTYESIF SHFREYEIAI RKVPGNFTFT HKKVKHENFS LLTSGEVGEF CVQVKPSVAS RSNKGMWSKE ECISLTRQYF TVTN

Specificity: His22-Asn235

Sterility: 0.22 μm filtered

Endotoxin Level: <0.1EU/μg

Biological Activity Comment: Measured by its binding ability in a functional ELISA.Immobilized Human IL10 at 2 μg/mL (100 μL/well) can bind Human IL10RA with a linear range of 0.1-8.7 ng/mL.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Target Details

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Alternative Name: IL-10 R alpha/IL10RA/CD210 (IL10RA Products)

Synonyms: IL10R1 Protein, IL10RA Protein, CD210 Protein, CD210a Protein, CDW210A Protein, HIL-10R Protein, IL-10R1 Protein, IL10R Protein, AW553859 Protein, CDw210 Protein, CDw210a Protein, Il10r Protein, mIL-10R Protein, interleukin 10 receptor subunit alpha Protein, interleukin 10 receptor, alpha Protein, IL10RA Protein, Il10ra Protein

Background:

Description: IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other, not protein-coding have been found for this gene. CD210 belongs to the type II cytokine receptor family. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines.

Name: CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1,IL10RA

Gene ID: 3587

UniProt: Q13651

Pathways: Growth Factor Binding