IL-1 beta Protein
Quick Overview for IL-1 beta Protein (ABIN7849691)
Target
See all IL-1 beta (IL1B) ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Purpose
- Recombinant Human IL-1b Protein
-
Sterility
- 0.2 μm filtered
-
Endotoxin Level
- <0.01 EU/μg by LAL test
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
-
Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 8 % Trehalose, 4 % Mannitol, 0.02 % Tween-80, pH 7.4.
-
Storage
- 4 °C,-20 °C,-80 °C
-
Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
-
-
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
-
Alternative Name
- IL-1b
-
Background
-
Synonyms: IL1B, IL-1, IL1-BETA, IL1F2, interleukin 1 beta, IL1beta
Description: Recombinant human IL-1b is produced by the E.coli system, with the target gene encoding Ala117-Ser269 expressed.
Background: Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene.There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1β.
-
UniProt
- P01584
-
Pathways
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
Target
-