IL12 Protein
Quick Overview for IL12 Protein (ABIN7849697)
Target
See all IL12 ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human IL-12 Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <0.01 EU/μg by LAL test
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Interleukin 12 (IL12) (AA 23-328) (Active) protein (His-Avi Tag)
IL12 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 12 (IL12) (AA 23-328) (Active) protein (Biotin,His-Avi Tag)IL12 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 12 (IL12) (AA 23-219), (AA 23-328) (Active) proteinIL12 Origin: Human Host: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,DYKDDDDK Tag)IL12 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag,AVI tag,DYKDDDDK Tag,Biotin)IL12 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 12 (IL12) proteinIL12 Origin: Human Host: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. AM, ADA, IA, ScA
Interleukin 12 (IL12) (AA 23-219) protein (His tag,Fc Tag)IL12 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 12 (IL12) (AA 23-328) (Active) protein (His tag)IL12 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS, AcA Active
Interleukin 12 (IL12) (AA 23-215), (AA 23-335) proteinIL12 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 12 (IL12) (AA 23-219) protein (His tag)IL12 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- IL12 (Interleukin 12 (IL12))
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Alternative Name
- IL-12
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Background
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Synonyms: Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35, NK cell, IL12A , NKSF1 stimulatory factor chain 1
Description: Recombinant human IL-12 is produced by the mammalian system, with the target gene encoding Arg23-Ser219& Ile23-Ser328 expressed.
Background: Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells,macrophages, neutrophils, helper T cells and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 belongs to the family of interleukin-12. IL-12 family is unique in comprising the only heterodimeric cytokines, which includes IL-12, IL-23, IL-27 and IL-35.Despite sharing many structural features and molecular partners, they mediate surprisingly diverse functional effects.
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UniProt
- P29459, P29460
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Pathways
- JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
Target
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