SIRT1 Protein (His tag)

Catalog No. ABIN7936232

This Recombinant SIRT1 protein is produced in Escherichia coli (E. coli).

Quick Overview for SIRT1 Protein (His tag) (ABIN7936232)

Target: SIRT1 (Sirtuin 1 (SIRT1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: Greater than 90 % as determined by SDS-PAGE.

Product Details

Purification tag / Conjugate: This SIRT1 protein is labelled with His tag.

Purpose: Recombinant Human NAD-dependent protein deacetylase sirtuin-1(SIRT1)

Sequence: ADEAALALQP GGSPSAAGAD REAASSPAGE PLRKRPRRDG PGLERSPGEP GGAAPEREVP AAARGCPGAA AAALWREAEA EAAAAGGEQE AQATAAAGEG DNGPGLQGPS REPPLADNLY DEDDDDEGEE EEEAAAAAIG YRDNLLFGDE IITNGFHSCE SDEEDRASHA SSSDWTPRPR IGPYTFVQQH LMIGTDPRTI LKDLLPETIP PPELDDMTLW QIVINILSEP PKRKKRKDIN TIEDAVKLLQ ECKKIIVLTG AGVSVSCGIP DFRSRDGIYA RLAVDFPDLP DPQAMFDIEY FRKDPRPFFK FAKEIYPGQF QPSLCHKFIA LSDKEGKLLR NYTQNIDTLE QVAGIQRIIQ CHGSFATASC LICKYKVDCE AVRGDIFNQV VPRCPRCPAD EPLAIMKPEI VFFGENLPEQ FHRAMKYDKD EVDLLIVIGS SLKVRPVALI PSSIPHEVPQ ILINREPLPH LHFDVELLGD CDVIINELCH RLGGEYAKLC CNPVKLSEIT EKPPRTQKEL AYLSELPPTP LHVSEDSSSP ERTSPPDSSV IVTLLDQAAK SNDDLDVSES KGCMEEKPQE VQTSRNVESI AEQMENPDLK NVGSSTGEKN ERTSVAGTVR KCWPNRVAKE QISRRLDGNQ YLFLPPNRYI FHGAEVYSDS EDDVLSSSSC GSNSDSGTCQ SPSLEEPMED ESEIEEFYNG LEDEPDVPER AGGAGFGTDG DDQEAINEAI SVKQEVTDMN YPSNKS

Characteristics: N-terminal 6xHis-tagged

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris-based buffer50 % glycerol

Storage: -20 °C,-80 °C

Storage Comment: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Expiry Date: 6-12 months

Target Details

Target: SIRT1 (Sirtuin 1 (SIRT1))

Alternative Name: NAD-dependent protein deacetylase sirtuin-1

Molecular Weight: 85.5 kDa

Gene ID: 23411

UniProt: Q96EB6

Pathways: MAPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling