FGF18 Protein
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- Target See all FGF18 Proteins
- FGF18 (Fibroblast Growth Factor 18 (FGF18))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR
- Characteristics
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Purified recombinant Human FGF18 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ? 0.5 ng/mL, corresponding to a specific activity of ? 2 x 10^6 units/mg. - Purity
- > 95 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product FGF18 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- Lyophilized from 10 mM Tris, pH 8.0, with 20 mM NaCl.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- FGF18 (Fibroblast Growth Factor 18 (FGF18))
- Alternative Name
- FGF18 (FGF18 Products)
- Synonyms
- FGF-18 Protein, ZFGF5 Protein, D130055P09Rik Protein, fgf18 Protein, FGF18 Protein, fgf18l Protein, fibroblast growth factor 18 Protein, fibroblast growth factor 18a Protein, fibroblast growth factor 18b Protein, FGF18 Protein, Fgf18 Protein, fgf18a Protein, Tsp_09844 Protein, fgf18b Protein
- Background
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FGF18 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF18 is an essential regulator of long bone and calvarial development. FGF18 signals through FGFR 1c, 2c, 3c, and 4.
Alternative Names: FGFI protein, FGF18, FGF 18 protein, FGF-18, FGF-18 protein, FGF 18, FGF-18 protein, Fibroblast Growth Factor-18 protein, zFGF5 protein - Molecular Weight
- 20.1 kDa
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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