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Thymic Stromal Lymphopoietin Protein (TSLP)

TSLP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure
Catalog No. ABIN935841
  • Target See all Thymic Stromal Lymphopoietin (TSLP) Proteins
    Thymic Stromal Lymphopoietin (TSLP)
    Protein Type
    Recombinant
    Origin
    • 25
    • 10
    • 5
    • 3
    Human
    Source
    • 17
    • 17
    • 4
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKE MFAMKTKAAL AIWCPGYSET QINATQAMKK RRKRKVTTNK CLEQVSQLQG L WRRFNRPL LKQQ
    Characteristics
    Purified recombinant Human TSLP protein
    Expression System: E.coli
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product TSLP Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
    Buffer
    Lyophilized from NaC2H3O2, pH 6.0.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    Thymic Stromal Lymphopoietin (TSLP)
    Alternative Name
    TSLP (TSLP Products)
    Synonyms
    TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
    Background
    TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL7 and binds with the heterodimeric receptor complex consisting of the IL7R alpha chain (IL7Ra) and the TSLP-specific chain (TSLPR). Like IL7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs).
    Alternative Names: Thymic Stromal Lymphopoietin protein, TSLP protein
    Molecular Weight
    15.0 kDa
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