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|Antigen||Bone Morphogenetic Protein 2 (BMP2) Antibodies|
|Epitope||AA 283-396 Alternatives|
|Conjugate||This BMP2 antibody is un-conjugated Alternatives|
ELISA, Immunoprecipitation (IP), Western Blotting (WB)
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Product Details anti-BMP2 AntibodyTarget Details BMP2 Application Details Handling Images
No cross-reactivity in ELISA with
E.coli cell lysate
|No Cross-Reactivity||Human, Escherichia coli (E. coli)|
|Characteristics||This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP-2 (rh BMP-2 , ABIN2002827 NP_001191.1, Gln 283-Arg 396,. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.|
|Purification||purified by Protein A affinity chromatography|
|Sterility||0.2 μm filtered|
|Immunogen||Recombinant Human BMP-2 protein (ABIN2002827)|
|Plasmids, Primers & others|
Target Details BMP2Product Details anti-BMP2 Antibody Application Details Handling Images back to top
|Alternative Name||BMP2 (BMP2 Antibody Abstract)|
|Background||BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.|
|Pathways||Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation|
Application DetailsProduct Details anti-BMP2 Antibody Target Details BMP2 Handling Images back to top
WB: 5-20 μg/mL
ELISA: 0.5-1 μg/mL
This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human BMP2. The detection limit for Human BMP2 is approximately 0.078 ng/well.
IP: 1-4 μL/mg of lysate
|Restrictions||For Research Use only|
HandlingProduct Details anti-BMP2 Antibody Target Details BMP2 Application Details Images back to top
|Buffer||0.2 μm filtered solution in PBS with 5 % trehalose|
|Handling Advice||Avoid repeated freeze-thaw cycles.|
|Storage||4 °C,-20 °C,-80 °C|
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
|Expiry Date||12 months|