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General |
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Antigen | Lysine (K)-Specific Demethylase 1A (KDM1A) Antibodies |
Reactivity | Human, Monkey, Mouse (Murine) Alternatives |
Host | Mouse Alternatives |
Clonality (Clone) | |
Conjugate | Un-conjugated Alternatives |
Application |
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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Specificity | This antibody reacts to LSD1/AOF2. |
Cross-Reactivity (Details) | Species reactivity (tested):Human, Mouse and Monkey. |
Purification | Ascites |
Clone | 1B2E5 |
Isotype | IgG1 |
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Antigen | |
Alternative Name | AOF2 (KDM1A Antibody Abstract) |
Background | The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.Synonyms: BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2, KIAA0601, LSD1, Lysine-specific histone demethylase 1 |
Molecular Weight | 93 kDa |
Gene ID | 23028 |
Pathways | Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling |
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Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
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Format | Liquid |
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