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CD24, a cell surface receptor enriched in both juvenile chondrocytes and human induced pluripotent stem cells-derived chondrocytes, is a regulatory factor in both faster proliferation and resistance to proinflammatory cues in these chondrocyte populations.
based on our data, the markers CD44 (show CD44 Proteins) and CD24 do not reflect the features of CSC and unfavorable prognosis and do not clarify the role and clinical significance of the immunophenotype CD44 (show CD44 Proteins)+/CD24-.
CD24 and CD44 (show CD44 Proteins) are upregulated in human pancreatic cancer compared to chronic pancreatitis and may be related to the development of pancreatic cancer.
Both in vitro and in vivo studies show that cells with CD24-knockdown are more sensitive to docetaxel, while CD24-overexpressing cells are more sensitive to doxorubicin
We believe that CD24 is a key molecule of metastatic progression in the epithelial-mesenchymal-transition phenomenon and a promising therapeutic target for advanced ovarian cancer.
CD133+CD24lo phenotype defines 5-FU-resistant human colon cancer stem cell-like cells.
Our results suggest that higher CD24 expression is significantly associated with lower OS rate, lower DFS (show FST Proteins) rate and some clinicopathological factors such as lymph node invasion and TNM (show ODZ1 Proteins) stage. This meta-analysis suggested that CD24 is an efficient prognostic factor in breast cancer
G7mAb was an anti-CD24 antibody.
CD44 (show CD44 Proteins) and CD24 collaboratively drive the reprogramming of nasopharyngeal carcinoma cells through STAT3 (show STAT3 Proteins)-mediated stemness and epithelial-mesenchymal transition activation
The increase in CD19 (show CD19 Proteins)+CD24+CD27 (show CD27 Proteins)+ Bregs was closely associated with fasting insulin (show INS Proteins) secretion.
CD24 has a role in determining the epithelial phenotype of pancreatic cancer
While no obvious role was found for CD24 in the normal development and maintenance of the dopaminergic nigrostriatal system in mice, it may have a role in mediating the neuroprotective aspects of GDNF in this system.
CD24 cell surface expression may serve as a valuable biomarker in order to identify mammary tumors that will positively respond to targeted IGF1R (show IGF1R Proteins) therapies.
mice negative or positive for CD24 did not differ in terms of tumor initiation and burden in 3 mammary and prostate tumor models tested, except for Apc1572T/+ mice, in which lack of CD24 reduced the mammary tumor burden slightly but significantly.
Loss of CD24 in Mice Leads to Metabolic Dysfunctions and a Reduction in White Adipocyte Tissue.
CD24 controls breast cancer radiation response. Loss of CD24 expression leads to radiation resistance.
Delayed wound-healing in the absence of HSA/CD24 suggests that CD24 plays an important role in this process
Findings indicate that CD24(+) antigen cells play a role in tumor migration and metastasis and support Janus kinase 2 (show JAK2 Proteins) protein (JAK2 (show JAK2 Proteins)) as a therapeutic target in ovarian cancer.
CD24 is a conserved marker for tracking divergent states in both reprogramming and standard pluripotent culture.
CD24 in non-immune cells might be crucialfor the guidance and recruitment of leukocytes.
This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and in many B cells. The encoded protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface.
CD24 antigen (small cell lung carcinoma cluster 4 antigen)
, signal transducer CD24
, CD24 antigen
, heat-stable antigen
, nectadrin heat stable antigen
, M1/69-J11D heat stable antigen
, X62 heat stable antigen
, cluster of differentiation 24
, heat stable antigen
, lymphocyte antigen 52