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anti-Rat (Rattus) DPYD Antibodies:
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Human Monoclonal DPYD Primary Antibody for IF, ELISA - ABIN560640
Kuilenburg, Meijer, Tanck, Dobritzsch, Zoetekouw, Dekkers, Roelofsen, Meinsma, Wymenga, Kulik, Büchel, Hennekam, Largiadèr: Phenotypic and clinical implications of variants in the dihydropyrimidine dehydrogenase gene. in Biochimica et biophysica acta 2016
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
, dihydropyrimidine dehydrogenase [NADP(+)]
, dihydrothymine dehydrogenase
, dihydrouracil dehydrogenase
, dihydropyrimidine dehydrogenase