We are preparing the requested document. Please wait, this may take a while...!
|Antigen||EPH Receptor B1 (EPHB1) Antibodies|
|Conjugate||This EPH Receptor B1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-EPH Receptor B1 AntibodyTarget Details EPH Receptor B1 Application Details Handling References for anti-EPH Receptor B1 antibody (ABIN359811) Images
|Specificity||This antibody reacts to EphB1.|
|Purification||Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a his tag recombinant protein of human EphB1.|
Target Details EPH Receptor B1Product Details anti-EPH Receptor B1 Antibody Application Details Handling References for anti-EPH Receptor B1 antibody (ABIN359811) Images back to top
|Alternative Name||EPHB1 (EPHB1 Antibody Abstract)|
|Background||Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: ELK, EPH2, EPHT2, Ephrin type-B receptor 1, HEK6, NET, Tyrosine-protein kinase receptor EPH-2|
|Gene ID||2047, 9606|
Application DetailsProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Handling References for anti-EPH Receptor B1 antibody (ABIN359811) Images back to top
ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Application Details References for anti-EPH Receptor B1 antibody (ABIN359811) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-EPH Receptor B1 antibody (ABIN359811)Product Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Application Details Handling Images back to top
Prevost, Woulfe, Tanaka, Brass: "Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9219-24, 2002
Wilkinson: "Multiple roles of EPH receptors and ephrins in neural development." in: Nature reviews. Neuroscience, Vol. 2, Issue 3, pp. 155-64, 2001
Xu, Mellitzer, Wilkinson: "Roles of Eph receptors and ephrins in segmental patterning." in: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 355, Issue 1399, pp. 993-1002, 2000
Jordan, Solan, Dominguez, Sia, Hand, Lampe, Laird: "Trafficking, assembly, and function of a connexin43-green fluorescent protein chimera in live mammalian cells." in: Molecular biology of the cell, Vol. 10, Issue 6, pp. 2033-50, 1999
Stein, Huynh-Do, Lane, Cerretti, Daniel: "Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase." in: The Journal of biological chemistry, Vol. 273, Issue 3, pp. 1303-8, 1998
ImagesProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Application Details Handling References for anti-EPH Receptor B1 antibody (ABIN359811) back to top