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|Antigen||EPH Receptor B1 (EPHB1) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This EPH Receptor B1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-EPH Receptor B1 AntibodyTarget Details EPH Receptor B1 Application Details Handling References for anti-EPH Receptor B1 antibody (ABIN359810) Images
|Specificity||This antibody reacts to EPHB1|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human EphB1.|
Target Details EPH Receptor B1Product Details anti-EPH Receptor B1 Antibody Application Details Handling References for anti-EPH Receptor B1 antibody (ABIN359810) Images back to top
|Alternative Name||EPHB1 (EPHB1 Antibody Abstract)|
|Background||Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: ELK, EPH2, EPHT2, Ephrin type-B receptor 1, HEK6, NET, Tyrosine-protein kinase receptor EPH-2|
|Gene ID||2047, 9606|
Application DetailsProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Handling References for anti-EPH Receptor B1 antibody (ABIN359810) Images back to top
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Application Details References for anti-EPH Receptor B1 antibody (ABIN359810) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-EPH Receptor B1 antibody (ABIN359810)Product Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Application Details Handling Images back to top
Sheng, Wang, Dong, Ma, Zhou, Sugimura, Lu, Zhou: "EphB1 is underexpressed in poorly differentiated colorectal cancers." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 75, Issue 5, pp. 274-80, 2008
ImagesProduct Details anti-EPH Receptor B1 Antibody Target Details EPH Receptor B1 Application Details Handling References for anti-EPH Receptor B1 antibody (ABIN359810) back to top