anti-Mouse (Murine) FLT1 antibody for Immunoprecipitation

Recommended FLT1 Antibody (supplied by: Log in to see )

Antigen
Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Antibodies
  • FLT
  • FLT-1
  • VEGFR-1
  • VEGFR1
  • FLT1
  • flt1b
  • sFlt1
  • AI323757
  • Flt-1
  • fms related tyrosine kinase 1
  • FMS-related tyrosine kinase 1
  • vascular endothelial growth factor receptor 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • FMS-like tyrosine kinase 1
  • FLT1
  • Flt1
  • CpipJ_CPIJ012087
  • flt1
Epitope
Extracellular Domain
49
37
17
16
14
13
13
12
11
8
7
6
5
5
5
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
483
159
109
21
17
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Host
Mouse
290
249
34
5
3
1
Clonality
Monoclonal
Conjugate
This FLT1 antibody is un-conjugated
38
21
14
13
13
12
12
10
10
9
8
8
8
8
8
8
5
5
5
5
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
349
222
150
117
99
79
64
41
22
13
12
9
7
4
3
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN115152
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN269286 ICC IF IP ELISA WB Mouse IgG1 Log in to see EWF 0
1 ABIN115153 EIA IF IP WB Mouse IgG1 Extracellular Domain Log in to see FLTEWI (EWI) 3
1 ABIN155162 EIA IF IP WB Biotin Mouse IgG1 Extracellular Domain Log in to see FLTEWF 0
1 ABIN360860 EIA IP WB Biotin Mouse IgG1 Log in to see FLTEWC 0
1 ABIN115150 EIA IP WB Mouse IgG1 Log in to see FLTEWC 0
1 ABIN449640 IP ELISA Biotin Mouse IgG1 Log in to see Flt-1-EWC 0
1 ABIN449641 IP ELISA Biotin Mouse IgG1 Log in to see Flt-1-EWC 0
1 ABIN4251383 ELISA ICC IF IP WB PerCP Mouse IgG1 Log in to see EWF 0
1 ABIN4251382 ELISA ICC IF IP WB PE Mouse IgG1 Log in to see EWF 0
1 ABIN4251384 ELISA ICC IF IP WB APC Mouse IgG1 Log in to see EWF 0
1 ABIN5703810 ELISA IF IP WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2905480 IF/ICC IHC IP WB Rabbit AA 27-329 Log in to see Polyclonal 0
1 ABIN5542025 EIA IP WB Biotin Mouse IgG1 Log in to see FLTEWI (EWI) 0
1 ABIN5927748 ELISA IF/ICC IP WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6035744 IF/ICC IHC IP WB Rabbit Log in to see Polyclonal 0

General

Antigen Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Antibodies
Epitope Extracellular Domain
(49), (37), (17), (16), (14), (13), (13), (12), (11), (8), (7), (6), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(483), (159), (109), (21), (17), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(290), (249), (34), (5), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FLT1 antibody is un-conjugated
(38), (21), (14), (13), (13), (12), (12), (10), (10), (9), (8), (8), (8), (8), (8), (8), (5), (5), (5), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(349), (222), (150), (117), (99), (79), (64), (41), (22), (13), (12), (9), (7), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-FLT1 Antibody

Target Details FLT1 Application Details Handling References for anti-FLT1 antibody (ABIN115152) Images
Specificity The monoclonal antibody will recognize recombinant and naturally occurring form of Human VEGFR-1/Flt-1.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Affinity Chromatography on Protein G
Immunogen Recombinant Human soluble extracellular Flt-1 protein (D5) (Cat.-No DA3539)
Clone FLTEWF
Isotype IgG1
Plasmids, Primers & others

Target Details FLT1

Product Details anti-FLT1 Antibody Application Details Handling References for anti-FLT1 antibody (ABIN115152) Images back to top
Antigen
Alternative Name VEGFR-1 / Flt-1 (FLT1 Antibody Abstract)
Background Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes, dendritic cells and on trophoblast cells. The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular splited tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher affinity for VEGF but a weaker signaling activity. VEGFR-1 thus leads not to proliferation of endothelial cells, but mediates signals for differentiation. Interestingly a naturally occuring soluble variant of VEGFR-1 (sVEGFR-1) was found in HUVE supernatants in 1996, which is generated by alternative splicing of the flt-1 mRNA.Synonyms: FLT, FLT1, FRT, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
Gene ID 2321
NCBI Accession NP_001153392
UniProt P17948
Pathways RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals

Application Details

Product Details anti-FLT1 Antibody Target Details FLT1 Handling References for anti-FLT1 antibody (ABIN115152) Images back to top
Application Notes ELISA (1.5-8 μg/mL), Western blotting (1-10 μg/mL), Immunoprecipitation (1-5 μg/mL lysateor reaction volume).
Other applications not tested.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FLT1 Antibody Target Details FLT1 Application Details References for anti-FLT1 antibody (ABIN115152) Images back to top
Reconstitution Restore with distilled sterile water to a concentration of 0.1-1.0 mg/mL.
Buffer PBS pH 7.4 containing no preservative
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-FLT1 antibody (ABIN115152)

Product Details anti-FLT1 Antibody Target Details FLT1 Application Details Handling Images back to top
Background publications

Roeckl, Hecht, Sztajer, Waltenberger, Yayon, Weich: "Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2." in: Experimental cell research, Vol. 241, Issue 1, pp. 161-70, 1998

Barleon, Totzke, Herzog, Blanke, Kremmer, Siemeister, Marmé, Martiny-Baron: "Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1." in: The Journal of biological chemistry, Vol. 272, Issue 16, pp. 10382-8, 1997

Chi, Hsieh, Hui, Tam: "Modified method for double stranded DNA sequencing and synthetic oligonucleotide purification." in: Nucleic acids research, Vol. 16, Issue 21, pp. 10382, 1989