anti-Human HER2 antibody for Immunofluorescence

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • wu:fv70f10
  • zgc:63601
  • erb2
  • erb-b2 receptor tyrosine kinase 2
  • ERBB2
  • Erbb2
  • erbb2
Epitope
AA 661-710, pThr686
103
94
71
69
60
55
54
48
46
35
26
22
21
21
20
20
20
20
20
20
20
20
20
19
19
19
17
17
15
15
15
13
13
12
11
8
8
8
8
8
7
7
6
6
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1370
490
319
36
34
15
13
8
6
5
4
3
3
3
2
1
1
1
1
1
Host
Rabbit
1002
511
32
16
12
5
2
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
76
66
59
56
55
41
19
19
12
12
11
10
10
8
8
8
8
8
7
7
7
7
7
7
7
7
6
3
2
2
Application
Immunofluorescence (IF), ELISA
712
603
318
314
309
303
269
133
112
102
89
21
19
18
8
6
6
5
3
3
3
2
1
1
1
1
1
1
1
Options
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Catalog No. ABIN1531590
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.964321 ABIN1534423 IF IHC ELISA WB Rabbit IgG AA 641-690 Log in to see Polyclonal 1
11.964321 ABIN1532607 IF ELISA Rabbit IgG AA 661-710 Log in to see Polyclonal 3
11.964321 ABIN4309121 ICC IF IHC IHC (p) WB Rabbit pTyr1248 Log in to see Polyclonal 2
11.964321 ABIN967786 IF IP IHC WB Mouse IgG2b AA 182-373 Log in to see 42-c-erbB 5
11.964321 ABIN967787 IF IP IHC WB Mouse IgG2b AA 182-373 Log in to see 42-c-erbB 5
11.964321 ABIN2957598 IC IF IHC WB Rabbit Log in to see Polyclonal
11.964321 ABIN1532624 IF ELISA Rabbit IgG AA 1111-1160 Log in to see Polyclonal
11.964321 ABIN4309125 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 2
11.964321 ABIN1881312 DB IF WB Rabbit pTyr1005 Log in to see Polyclonal 3
11.964321 ABIN1881313 DB IF WB Rabbit pTyr1196 Log in to see Polyclonal 3
11.964321 ABIN2454964 FACS IF IHC WB Mouse IgG2a AA 676-1255 Log in to see 4F10
11.964321 ABIN2455003 IF IHC WB Mouse IgG2b AA 676-1255 Log in to see 1D9
11.964321 ABIN2455010 IF IHC WB Mouse IgG2a AA 676-1255 Log in to see 11A7
11.964321 ABIN2455012 FACS IF IHC WB Mouse IgG2b AA 676-1255 Log in to see 9G2
11.964321 ABIN2455011 FACS IF IHC WB Mouse IgG2b AA 676-1255 Log in to see 3F11
11.964321 ABIN2455013 IF IHC WB Mouse IgG2a AA 676-1255 Log in to see 12G4
11.964321 ABIN2455009 FACS IF IHC WB Mouse IgG2a AA 676-1255 Log in to see 1C5
11.964321 ABIN4309119 ICC IF IHC IHC (p) WB Rabbit pTyr877 Log in to see Polyclonal
11.964321 ABIN782315 EIA IF IHC (p) WB Mouse IgG2b Log in to see 4-00E-001
11.964321 ABIN4309122 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope AA 661-710, pThr686
(103), (94), (71), (69), (60), (55), (54), (48), (46), (35), (26), (22), (21), (21), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (19), (19), (17), (17), (15), (15), (15), (13), (13), (12), (11), (8), (8), (8), (8), (8), (7), (7), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(1370), (490), (319), (36), (34), (15), (13), (8), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(1002), (511), (32), (16), (12), (5), (2)
Clonality
Polyclonal
Conjugate This HER2 antibody is un-conjugated
(76), (66), (59), (56), (55), (41), (19), (19), (12), (12), (11), (10), (10), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (3), (2), (2)
Application Immunofluorescence (IF), ELISA
(712), (603), (318), (314), (309), (303), (269), (133), (112), (102), (89), (21), (19), (18), (8), (6), (6), (5), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN1531590) Images
Specificity

HER2 (Phospho-Thr686) Antibody detects endogenous levels of HER2 only when phosphorylated at Thr686.

PhosphorylationH:T686 M:T687 R:T688

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Immunogen The antiserum was produced against synthesized peptide derived from human HER2 around the phosphorylation site of Thr686.
Isotype IgG

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 antibody (ABIN1531590) Images back to top
Antigen
Alternative Name HER2 (ERBB2 Antibody Abstract)
Background

Synonyms: C-erbB-2, Epidermal growth factor receptor-related protein, ErbB2, HER2, MLN 19, NEU, NEU proto-oncogene, NGL, Receptor protein-tyrosine kinase erbB-2, Receptor protein-tyrosine kinase erbB-2 precursor, Tyrosine kinase-type cell surface receptor HER2, kin

NCBI Gene Symbol: ERBB2

Molecular Weight 137 kDa
Gene ID 2064
OMIM 164870
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 antibody (ABIN1531590) Images back to top
Application Notes IF: 1:100~1:500 ELISA: 1:5000
Comment

Unigene-Number: Hs.446352 (NCBI Gene Symbol: ERBB2)

Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 antibody (ABIN1531590) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months

References for anti-HER2 antibody (ABIN1531590)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Background publications

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006

Yamamoto, Ikawa, Akiyama, Semba, Nomura, Miyajima, Saito, Toyoshima: "Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor." in: Nature, Vol. 319, Issue 6050, pp. 230-4, 1986

King, Kraus, Aaronson: "Amplification of a novel v-erbB-related gene in a human mammary carcinoma." in: Science (New York, N.Y.), Vol. 229, Issue 4717, pp. 974-6, 1985

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN1531590) back to top
Supplier Images
Immunofluorescence (IF) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (AA 661-710), (pThr686) antibody (ABIN1531590) Immunofluorescence analysis of HuvEc cells, using HER2 (Phospho-Thr686) Antibody. The...