anti-Mouse (Murine) HER2 antibody for Immunocytochemistry

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • wu:fv70f10
  • zgc:63601
  • erb2
  • erb-b2 receptor tyrosine kinase 2
  • ERBB2
  • Erbb2
  • erbb2
Epitope
pTyr1248
128
86
70
67
59
49
48
35
30
30
25
22
21
16
15
15
13
13
12
12
11
11
11
11
11
11
11
11
11
11
11
11
10
8
8
7
7
7
6
6
6
5
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1302
399
296
28
21
8
4
4
4
4
3
3
3
2
1
1
1
Host
Rabbit
786
587
29
14
11
3
3
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
59
45
44
42
41
27
20
20
13
13
13
13
11
11
8
8
8
8
8
7
7
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
3
2
2
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
668
466
429
396
341
201
197
102
102
101
86
47
24
21
18
11
6
4
3
3
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN4309121
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4309119 ICC IF IHC IHC (p) WB Rabbit pTyr877 Log in to see Polyclonal 1
1 ABIN295912 ICC IHC IHC (p) WB Chicken IgY AA 153-433 Log in to see Polyclonal 0
1 ABIN4309122 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal 0
1 ABIN2467831 ICC IHC WB Chicken AA 153-433 Log in to see Polyclonal 0
1 ABIN2469599 ICC IHC WB Chicken IgY AA 153-433 Log in to see Polyclonal 0
1 ABIN5541738 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 AA 1242-1255, C-Term Log in to see 3B5 0

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope pTyr1248
(128), (86), (70), (67), (59), (49), (48), (35), (30), (30), (25), (22), (21), (16), (15), (15), (13), (13), (12), (12), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (10), (8), (8), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(1302), (399), (296), (28), (21), (8), (4), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1)
Host Rabbit
(786), (587), (29), (14), (11), (3), (3)
Clonality
Polyclonal
Conjugate This HER2 antibody is un-conjugated
(59), (45), (44), (42), (41), (27), (20), (20), (13), (13), (13), (13), (11), (11), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (3), (2), (2), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(668), (466), (429), (396), (341), (201), (197), (102), (102), (101), (86), (47), (24), (21), (18), (11), (6), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN4309121) Images
Specificity HER2 (specific to Phospho-Tyr1248) detects endogenous levels of HER2 only when phosphorylated at tyrosine1248.
Purification Immunogen affinity purified
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine1248 (P-E-YP-L-G).
Plasmids, Primers & others

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 antibody (ABIN4309121) Images back to top
Antigen
Alternative Name ErbB2/Her2 (ERBB2 Antibody Abstract)
Background Gene Symbol: ERBB2
Molecular Weight Theoretical MW: 185 kDa
Gene ID 2064
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 antibody (ABIN4309121) Images back to top
Application Notes Western Blot 1:500-1:1000, Immunohistochemistry 1:50-1:100, Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunohistochemistry-Paraffin 1:50-1:100The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 antibody (ABIN4309121) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, and 50 % glycerol.
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

References for anti-HER2 antibody (ABIN4309121)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Product cited in:

Scrima, Zito Marino, Oliveira, Marinaro, La Mantia, Rocco, De Marco, Malanga, De Rosa, Rizzuto, Botti, Franco, Zoppoli, Viglietto: "Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients." in: Journal of Cancer, Vol. 8, Issue 2, pp. 227-239, 2017

Eden, Ju, Murugesan, Phoenix, Nimmervoll, Tong, Ellison, Finkelstein, Wright, Boulos, Dapper, Thiruvenkatam, Lessman, Taylor, Gilbertson: "Orthotopic models of pediatric brain tumors in zebrafish." in: Oncogene, Vol. 34, Issue 13, pp. 1736-42, 2015 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN4309121) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN4309121) Immunohistochemistry-Paraffin: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Human...
Western Blotting (WB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN4309121) Western Blot: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Analysis of extracts f...
Western Blotting (WB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN4309121) Western Blot: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Western blot analysis ...
Immunofluorescence (IF) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN4309121) Immunocytochemistry/Immunofluorescence: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210...
Western Blotting (WB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN4309121) Western Blot: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Analysis of extracts f...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody (ABIN4309121) Immunohistochemistry-Paraffin: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Human...