anti-Human IGF1R antibody for Immunohistochemistry

Recommended IGF1R Antibody (supplied by: Log in to see )

Antigen
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
  • CD221
  • IGFIR
  • IGFR
  • JTK13
  • IGFIRC
  • IGFR1
  • IGF-1R
  • IGF1R
  • DKFZp469I0618
  • igf-1r
  • xIGF-1R
  • xIGFR
  • xigf1r
  • A330103N21Rik
  • D930020L01
  • hyft
  • igf-ir
  • IGF-IRa
  • sb:eu1090
  • wu:fi20b10
  • insulin like growth factor 1 receptor
  • insulin-like growth factor 1 receptor
  • insulin-like growth factor I receptor
  • insulin like growth factor 1 receptor S homeolog
  • insulin-like growth factor 1a receptor
  • IGF1R
  • Igf1r
  • igf1r
  • LOC780503
  • LOC100136427
  • igf1r.S
  • igf1ra
Epitope
AA 1101-1367
49
45
42
40
29
28
26
22
18
17
16
15
15
15
13
13
10
9
8
7
7
7
7
6
6
5
5
4
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
580
334
312
26
20
19
18
16
13
12
5
3
2
2
2
1
Host
Mouse
451
129
2
2
1
Clonality
Monoclonal
Conjugate
This IGF1R antibody is un-conjugated
21
19
19
18
12
12
8
8
8
8
8
8
8
8
8
8
6
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
405
186
157
110
104
94
85
51
40
15
8
6
5
3
2
2
2
2
1
1
1
1
1
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Catalog No. ABIN969207
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
24.748539 ABIN932245 IHC ELISA WB Mouse IgG2a Log in to see 3G5C1 0
24.748539 ABIN3020253 IF IHC WB Rabbit pTyr1161 Log in to see Polyclonal 0
21.992775 ABIN6256637 ELISA ICC IF IHC WB Rabbit IgG pTyr1346 Log in to see Polyclonal 0
21.748539 ABIN932527 IHC ELISA WB Mouse IgG2b Log in to see 3C8B1 0
20.492775 ABIN6255780 ELISA ICC IF IHC WB Rabbit IgG pTyr1165, pTyr1166 Log in to see Polyclonal 1
18.992775 ABIN6256620 ELISA ICC IF IHC IP WB Rabbit IgG pTyr1161 Log in to see Polyclonal 0
18.755764 ABIN3185133 ELISA IHC WB Rabbit IgG Ser1026 Log in to see Polyclonal 0
18.755764 ABIN3182037 ELISA IHC IP WB Rabbit IgG pTyr1161 Log in to see Polyclonal 0
18.755764 ABIN926846 IHC WB Rabbit Middle Region Log in to see Polyclonal 0
17.492775 ABIN2792087 IF IHC WB Rabbit Middle Region Log in to see Polyclonal 2
17.255764 ABIN966345 IHC Rabbit Log in to see Polyclonal 1
17.255764 ABIN966343 IHC Rabbit pTyr1161 Log in to see 1
17.255764 ABIN966346 IHC Rabbit Log in to see Polyclonal 1
17.255764 ABIN966348 IHC ELISA WB IgG2b Log in to see 2
15.992776 ABIN6269831 ELISA IHC WB Rabbit IgG pThr1163 Log in to see Polyclonal 0
15.992776 ABIN6262491 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
15.992776 ABIN1848190 IHC ELISA WB Rabbit Tyr1346 Log in to see Polyclonal 0
15.755764 ABIN3182743 ELISA IF IHC WB Rabbit IgG pTyr1161 Log in to see Polyclonal 0
15.755764 ABIN3185141 ELISA IHC WB Rabbit IgG Ser528 Log in to see Polyclonal 0
12.992776 ABIN2704917 IC IF IP IHC WB Rabbit C-Term, pTyr1161 Log in to see Polyclonal 0

General

Antigen Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
Epitope AA 1101-1367
(49), (45), (42), (40), (29), (28), (26), (22), (18), (17), (16), (15), (15), (15), (13), (13), (10), (9), (8), (7), (7), (7), (7), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(580), (334), (312), (26), (20), (19), (18), (16), (13), (12), (5), (3), (2), (2), (2), (1)
Host Mouse
(451), (129), (2), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IGF1R antibody is un-conjugated
(21), (19), (19), (18), (12), (12), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (6), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(405), (186), (157), (110), (104), (94), (85), (51), (40), (15), (8), (6), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-IGF1R Antibody

Target Details IGF1R Application Details Handling References for anti-IGF1R antibody (ABIN969207) Images
Purification Ascites
Immunogen Purified recombinant fragment of IGF1R-Beta (AA 1101-1367) expressed in E. Coli.
Clone 3G5C1
Isotype IgG2a
Plasmids, Primers & others

Target Details IGF1R

Product Details anti-IGF1R Antibody Application Details Handling References for anti-IGF1R antibody (ABIN969207) Images back to top
Antigen
Alternative Name IGF1R (IGF1R Antibody Abstract)
Background IGF1R(insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.
Molecular Weight 96 kDa
Gene ID 3480
HGNC 3480
Pathways RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy

Application Details

Product Details anti-IGF1R Antibody Target Details IGF1R Handling References for anti-IGF1R antibody (ABIN969207) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details References for anti-IGF1R antibody (ABIN969207) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-IGF1R antibody (ABIN969207)

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling Images back to top
Product cited in:

Zhu, Jiang, Thompson: "Mechanisms by which energy restriction inhibits rat mammary carcinogenesis: in vivo effects of corticosterone on cell cycle machinery in mammary carcinomas." in: Carcinogenesis, Vol. 24, Issue 7, pp. 1225-31, 2003

Ling, Maile, Clemmons et al.: "Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for embrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 17, Issue 9, pp. 1824-33, 2003

Images

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling References for anti-IGF1R antibody (ABIN969207) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1101-1367) antibody (ABIN969207) Figure 1: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues us...
Immunohistochemistry (IHC) image for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1101-1367) antibody (ABIN969207) Figure 2: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues usi...
Western Blotting (WB) image for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1101-1367) antibody (ABIN969207) Figure 3: Western blot analysis using IGF1R-Beta mouse mAb against truncated IGF1R re...