anti-Human MME antibody for Immunohistochemistry

Recommended MME Antibody (supplied by: Log in to see )

Antigen
Membrane Metallo-Endopeptidase (MME) Antibodies
  • CALLA
  • CD10
  • NEP
  • SFE
  • 6030454K05Rik
  • C85356
  • Nep
  • neprilysin
  • membrane metalloendopeptidase
  • membrane metallo endopeptidase
  • membrane metallo-endopeptidase
  • MME
  • Mme
Epitope
AA 52-246
26
24
17
16
12
11
11
10
9
9
8
8
6
6
6
5
5
5
5
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
642
125
108
11
6
4
4
2
2
2
2
1
1
1
1
Host
Mouse
441
215
3
3
Clonality
Monoclonal
Conjugate
This MME antibody is un-conjugated
61
50
43
31
11
9
7
6
5
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
355
286
210
137
113
91
87
40
35
21
16
13
4
4
4
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN4880870
$ 561.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.404079 ABIN4880871 ELISA IHC WB Mouse IgG1 AA 52-246 Log in to see 5E9A5 0
8.404079 ABIN2869343 ELISA IHC WB Mouse IgG1 Log in to see 3G9D10 1
8.404079 ABIN1724914 IHC ELISA WB Mouse IgG1 AA 52-246 Log in to see 7D4B1 1
8.404079 ABIN1724916 IHC ELISA WB Mouse IgG1 AA 52-246 Log in to see 5E9A5 1
8.404079 ABIN2869165 ELISA IHC Mouse IgG2b Log in to see 2A1H5E1 0
8.404079 ABIN1175016 ICC IHC WB Rabbit IgG AA 382-538 Log in to see Polyclonal 0
8.404079 ABIN4338596 ELISA IHC IHC (p) WB Mouse IgG1 Log in to see 7D4B1 0
8.404079 ABIN4338595 ELISA IHC WB Mouse IgG1 Log in to see 5E9A5 0
8.404079 ABIN4900407 CyTOF ELISA (Capture) FACS IHC IP WB Goat IgG AA 52-750 Log in to see Polyclonal 3
8.404079 ABIN5611261 ELISA FACS IHC WB Mouse IgG1 AA 549-750 Log in to see 3G6B11 0
8.404079 ABIN6263285 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
8.404079 ABIN609735 IHC IHC (p) Mouse IgG1 Extracellular Log in to see 56C6 0
8.404079 ABIN4900406 ELISA (Detection) FACS IHC WB Biotin Goat IgG AA 52-750 Log in to see Polyclonal 0
8.404079 ABIN969011 IHC ELISA WB Mouse IgG1 Log in to see 3G9D10 2
8.404079 ABIN1724642 IHC ELISA Mouse IgG2b Log in to see 2A1H5E1 2
8.404079 ABIN2983280 IHC ELISA Mouse IgG2b Log in to see 0
8.404079 ABIN1913965 IHC IHC (fro) IHC (p) Rabbit N-Term Log in to see Polyclonal 0
8.404079 ABIN2588353 IF IHC IHC (p) WB Rabbit AA 274-302 Log in to see Polyclonal 0
8.404079 ABIN5027077 IHC WB Mouse IgG2b kappa AA 282-496 Log in to see ABM4A52 0
8.404079 ABIN1843072 IHC ELISA WB Mouse IgG1 Log in to see 0

General

Antigen Membrane Metallo-Endopeptidase (MME) Antibodies
Epitope AA 52-246
(26), (24), (17), (16), (12), (11), (11), (10), (9), (9), (8), (8), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(642), (125), (108), (11), (6), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(441), (215), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MME antibody is un-conjugated
(61), (50), (43), (31), (11), (9), (7), (6), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
(355), (286), (210), (137), (113), (91), (87), (40), (35), (21), (16), (13), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-MME Antibody

Target Details MME Application Details Handling Images
Purpose Purified Mouse Monoclonal Antibody
Characteristics This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene..

Synonyms: Neprilysin, 3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN
Purification Purified
Immunogen

Immunogen: Purified recombinant fragment of human CD10 (AA: 52-246) expressed in E. Coli.

Antigen Type: Recombinant Protein

Clone 7D4B1
Isotype IgG1
Plasmids, Primers & others

Target Details MME

Product Details anti-MME Antibody Application Details Handling Images back to top
Antigen
Alternative Name MME (MME Antibody Abstract)
Background

Other Names: Neprilysin, 3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN

Description: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

Molecular Weight 85514
Gene ID 4311
UniProt P08473
Pathways RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration

Application Details

Product Details anti-MME Antibody Target Details MME Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MME Antibody Target Details MME Application Details Images back to top
Format Liquid
Buffer Purified antibody in PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-MME Antibody Target Details MME Application Details Handling back to top
Supplier Images
ELISA image for anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody (ABIN4880870) Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (5...
Western Blotting (WB) image for anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody (ABIN4880870) Figure 1: Western blot analysis using CD10 mAb against human CD10 (AA: 52-246) recomb...
Western Blotting (WB) image for anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody (ABIN4880870) Figure 2: Western blot analysis using CD10 mAb against HEK293 (1) and CD10 (AA: 52-24...
Western Blotting (WB) image for anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody (ABIN4880870) Figure 3: Western blot analysis using CD10 mouse mAb against LNCAP cell lysate. Dilut...
Immunohistochemistry (IHC) image for anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody (ABIN4880870) Figure 4: Immunohistochemical analysis of paraffin-embedded prostate cancer tissues u...
Immunohistochemistry (IHC) image for anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody (ABIN4880870) Figure 5: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues u...