anti-Human MST1R antibody for Western Blotting

Recommended MST1R Antibody (supplied by: Log in to see )

Antigen
Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) Antibodies
  • CD136
  • CDw136
  • PTK8
  • RON
  • Fv-2
  • Fv2
  • Ron
  • STK
  • Cdw136
  • Ptk8
  • Stk
  • macrophage stimulating 1 receptor
  • macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • MST1R
  • Mst1r
Epitope
AA 22-51, C-Term, N-Term
30
28
22
17
17
15
15
15
7
7
7
6
5
5
4
3
3
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
189
71
37
3
2
1
1
Host
Rabbit
183
23
7
Clonality
Polyclonal
Conjugate
This MST1R antibody is un-conjugated
12
12
11
10
9
8
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Western Blotting (WB)
116
105
42
32
28
5
2
2
2
2
1
1
1
Options
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Catalog No. ABIN392048
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2563753 ABIN453814 EIA WB Rabbit AA 163-514 Log in to see Polyclonal 5
3.2563753 ABIN1531538 ELISA WB Rabbit IgG AA 1351-1400, pSer1394 Log in to see Polyclonal 0
3.2563753 ABIN652379 WB Rabbit Ig Fraction Log in to see Polyclonal 3
3.2563753 ABIN969384 ELISA WB Mouse IgG1 AA 210-320 Log in to see 1B5A9 3
3.2563753 ABIN1859891 ICC IHC WB Rabbit IgG AA 1092-1316 Log in to see Polyclonal 0
3.2563753 ABIN2650934 WB Rabbit IgG Log in to see Polyclonal 0
3.2563753 ABIN3182243 ELISA WB Rabbit IgG pSer1394 Log in to see Polyclonal 0
3.2563753 ABIN931390 ELISA WB Mouse IgG1 AA 210-320 Log in to see 1B5A9 0
3.2563753 ABIN1105858 WB Mouse IgG1 Log in to see 1B5A9 2
3.2563753 ABIN1844981 ELISA WB Mouse IgG1 AA 210-320 Log in to see 0
3.2563753 ABIN5596948 ELISA WB Rabbit IgG Internal Region, Tyr1360 Log in to see Polyclonal 0
3.2563753 ABIN5596949 ELISA WB Rabbit IgG Internal Region, pTyr1353 Log in to see Polyclonal 0
3.2563753 ABIN5596950 ELISA WB Rabbit IgG Internal Region, pTyr1360 Log in to see Polyclonal 0
3.2563753 ABIN5596947 ELISA WB Rabbit IgG Internal Region, Tyr1353 Log in to see Polyclonal 0
3.2563753 ABIN5663716 WB Rabbit Log in to see Polyclonal 0
1 ABIN359935 EIA WB Rabbit Ig Fraction N-Term, C-Term, AA 22-51 Log in to see Polyclonal 6
1 ABIN2869344 ELISA WB Mouse IgG1 AA 210-320 Log in to see 1B5A9 3
1 ABIN466815 ELISA WB Mouse IgG1 AA 210-320 Log in to see 1B5A9 0
1 ABIN5536954 WB Rabbit Ig Fraction C-Term, N-Term Log in to see Polyclonal 0
1 ABIN710336 IF (p) IHC (p) WB Rabbit IgG AA 1220-1260, pTyr1238 Log in to see Polyclonal 0

General

Antigen Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) Antibodies
Epitope AA 22-51, C-Term, N-Term
(30), (28), (22), (17), (17), (15), (15), (15), (7), (7), (7), (6), (5), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(189), (71), (37), (3), (2), (1), (1)
Host Rabbit
(183), (23), (7)
Clonality (Clone)
Polyclonal   ( )
Conjugate This MST1R antibody is un-conjugated
(12), (12), (11), (10), (9), (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Western Blotting (WB)
(116), (105), (42), (32), (28), (5), (2), (2), (2), (2), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-MST1R Antibody

Target Details MST1R Application Details Handling References for anti-MST1R antibody (ABIN392048) Images
Specificity This RON antibody is generated from rabbits immunized with two KLH conjugated synthetic peptides between 22~51 amino acids from the N-terminal and C-terminal regions of human RON.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This RON antibody is generated from rabbits immunized with two KLH conjugated synthetic peptides between 22-51 amino and 1370-1400 acids from the N-terminal and C-terminal regions of human RON.
Clone RB1356
Isotype Ig Fraction

Target Details MST1R

Product Details anti-MST1R Antibody Application Details Handling References for anti-MST1R antibody (ABIN392048) Images back to top
Antigen
Alternative Name RON (MST1R Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Synonyms: p185-Ron, CDW136, CD136 antigen, MST1R, RON, Macrophage-stimulating protein receptor alpha chain, Macrophage-stimulating protein receptor beta chain, Macrophage-stimulating protein receptor MSPR, MSP receptor
Molecular Weight 152227 DA
Gene ID 4486
UniProt Q04912
Pathways RTK Signaling

Application Details

Product Details anti-MST1R Antibody Target Details MST1R Handling References for anti-MST1R antibody (ABIN392048) Images back to top
Application Notes WB = 1:1000
Restrictions For Research Use only

Handling

Product Details anti-MST1R Antibody Target Details MST1R Application Details References for anti-MST1R antibody (ABIN392048) Images back to top
Format Liquid
Concentration 1.64 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-MST1R antibody (ABIN392048)

Product Details anti-MST1R Antibody Target Details MST1R Application Details Handling Images back to top
Product cited in:

Kobayashi, Furukawa, Kikuchi, Ito, Miyata, Muto, Tanaka, Kusano: "Transactivation of RON receptor tyrosine kinase by interaction with PDGF receptor beta during steady-state growth of human mesangial cells." in: Kidney international, Vol. 75, Issue 11, pp. 1173-83, 2009

Background publications

Penengo, Rubin, Yarden, Gaudino: "c-Cbl is a critical modulator of the Ron tyrosine kinase receptor." in: Oncogene, Vol. 22, Issue 24, pp. 3669-79, 2003

Zhou, He, Chen, Wang, Wang: "Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential." in: Oncogene, Vol. 22, Issue 2, pp. 186-97, 2003

Danilkovitch-Miagkova, Duh, Kuzmin, Angeloni, Liu, Miller, Lerman: "Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 8, pp. 4580-5, 2003

Images

Product Details anti-MST1R Antibody Target Details MST1R Application Details Handling References for anti-MST1R antibody (ABIN392048) back to top
Supplier Images
Western Blotting (WB) image for anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 22-51), (C-Term), (N-Term) antibody (ABIN392048) Western blot analysis of anti-RON Pab (ABIN392048) in THP1 cell lysate. RON (arrow) w...