SHC1 Proteins

(SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].

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SHC1 Protein (AA 1-583) (His tag)

custom-made SHC1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant SHC1 Protein, UniprotID P29353

3 images

Catalog No. ABIN7555478

Details

SHC1 Protein (AA 1-579) (His tag)

custom-made SHC1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Shc1 Protein, UniprotID P98083

3 images

Catalog No. ABIN7563568

Details

SHC1 Protein (AA 161-474) (His tag)

SHC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

Western Blotting (WB) image for SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (AA 161-474) protein (His tag) (ABIN7125084)

1 image

Catalog No. ABIN7125084

Details

SHC1 Protein (AA 1-474) (His tag)

SHC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

Western Blotting (WB) image for SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (AA 1-474) protein (His tag) (ABIN7125085)

1 image

Catalog No. ABIN7125085

Details

SHC1 Protein (AA 272-559) (His tag)

SHC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, PC, Imm

Catalog No. ABIN7398083

Details

SHC1 Protein

SHC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS

Catalog No. ABIN2131830

Details

SHC1 Protein (AA 1-579) (Strep Tag)

custom-made SHC1 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

Catalog No. ABIN3134740

Details

SHC1 Protein (AA 1-583) (Strep Tag)

custom-made SHC1 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

Catalog No. ABIN3095409