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SIRT1 Antibodies

(Sirtuin 1 (SIRT1))

SIRT1 (Sirtuin 1) is a protein that plays a role in regulating metabolism and has been implicated in the development and progression of obesity. Several studies have investigated the potential of targeting SIRT1 as a therapeutic strategy for obesity.

Research has shown that SIRT1 is involved in the regulation of nutrient sensing and can modulate lipid and glucose metabolism. It has been found to protect against high-fat diet-induced metabolic damage and hepatic lipid accumulation. SIRT1 has also been shown to promote lipid metabolism and mitochondrial function, which are important processes in adipogenesis and obesity.

In addition, SIRT1 has been found to counteract aging- and obesity-related diseases by deacetylating many proteins. It has been suggested that targeting SIRT1 activity in the brain may show promise for the treatment of obesity and associated metabolic disorders.

SIRT1 antibodies are essential research tools for better understanding the role of SIRT1 in in regulating metabolism, lipid metabolism, and mitochondrial function.

Active filters:

  • Target: SIRT1
  • Primary
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN5557342
Recombinant SIRT1 antibody (pThr530) SIRT1 · Primary Antibody Human Rabbit Monoclonal
  • IF (cc) (Immunofluorescence (Cultured Cells): Validation image available)
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): Listed application)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): Listed application)
$490.77 View price
  • 100 μL
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN185702
SIRT1 antibody (Internal Region) SIRT1 · Primary Antibody Mouse Goat Polyclonal
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
$488.25 View price
  • 100 μg
  • 20 μg
Delivery in 1 to 3 Business Days Shipping to: United States
ABIN625834
SIRT1 antibody (AA 577-590) SIRT1 · Primary Antibody Human Goat Polyclonal
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Validation image available)
  • ELISA (ELISA: Listed application)
$488.25 View price
  • 100 μg
Delivery in 1 to 3 Business Days Shipping to: United States
ABIN7435919
SIRT1 antibody (AA 238-482) SIRT1 · Primary Antibody Rat Rabbit Polyclonal
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • IP (Immunoprecipitation: Listed application)
$347.18 View price
  • 100 μL
  • 1 mL
  • 20 μL
  • 200 μL
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7270323
SIRT1 antibody (pSer47) SIRT1 · Primary Antibody Human Rabbit Monoclonal
  • WB (Western Blotting: Validation image available)
$393.00 View price
  • 100 μL
  • 1 mL
  • 20 μL
  • 500 μL
Delivery in 7 to 10 Business Days Shipping to: United States
ABIN1169086
SIRT1 antibody SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
$438.44 View price
  • 100 μg
  • 25 μg
Delivery in 5 to 10 Business Days Shipping to: United States
ABIN7427144
SIRT1 antibody (AA 238-482) SIRT1 · Primary Antibody Rat Mouse Monoclonal Clone D4
  • WB (Western Blotting: Validation image available)
$361.20 View price
  • 100 μL
  • 1 mL
  • 20 μL
  • 200 μL
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN3186962
SIRT1 antibody (Tyr631) SIRT1 · Primary Antibody Human, Mouse Rabbit Polyclonal
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
$413.63 View price
  • 100 μL
  • 50 μL
  • 200 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN8067573
SIRT1 antibody SIRT1 · Primary Antibody Human, Mouse Mouse Monoclonal Clone AFfirm8967
  • WB (Western Blotting: Validation image available)
$441.17 View price
  • 100 μL
  • 200 μL
Delivery in 11 to 13 Business Days Shipping to: United States
ABIN7426619
SIRT1 antibody (AA 244-498) SIRT1 · Primary Antibody Human Mouse Monoclonal Clone C2
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • IP (Immunoprecipitation: Listed application)
$340.17 View price
  • 100 μL
  • 1 mL
  • 20 μL
  • 200 μL
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN679028
SIRT1 antibody (AA 551-650) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • IHC (Immunohistochemistry: Validation image available)
  • WB (Western Blotting: Listed application)
  • FACS (Flow Cytometry: Listed application)
  • IF (cc) (Immunofluorescence (Cultured Cells): Listed application)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): Listed application)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): Listed application)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): Listed application)
$384.62 View price
  • 100 μL
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN565070
SIRT1 antibody (AA 456-555) SIRT1 · Primary Antibody Human Mouse Polyclonal
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
$350.04 View price
  • 50 μL
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN746003
SIRT1 antibody (pSer27) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • IHC (Immunohistochemistry: Validation image available)
  • WB (Western Blotting: Listed application)
  • FACS (Flow Cytometry: Listed application)
$384.62 View price
  • 100 μL
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN7308334
SIRT1 antibody SIRT1 · Primary Antibody Human, Mouse Rabbit Polyclonal
  • WB (Western Blotting: Validation image available)
  • IF (Immunofluorescence: Validation image available)
  • IHC (Immunohistochemistry: Validation image available)
  • IP (Immunoprecipitation: Listed application)
  • ChIP (Chromatin Immunoprecipitation: Listed application)
$330.77 View price
  • 100 μL
  • 30 μL
  • 50 μL
  • 200 μL
Delivery in 13 to 15 Business Days Shipping to: United States
ABIN6006096
SIRT1 antibody SIRT1 · Primary Antibody Human, Rat Rabbit Polyclonal
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Validation image available)
  • IF (Immunofluorescence: Validation image available)
  • IP (Immunoprecipitation: Listed application)
  • IF/ICC (Immunofluorescence (fixed cells): Listed application)
  • ChIP (Chromatin Immunoprecipitation: Listed application)
$472.66 View price
  • 100 μL
  • 50 μL
  • 200 μL
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN7571401
SIRT1 antibody (AA 194-747) SIRT1 · Primary Antibody Human, Rat Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
$317.38 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7126429
SIRT1 antibody SIRT1 · Primary Antibody Human Mouse Monoclonal Clone PCRP-SIRT1-1E11
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
  • FACS (Flow Cytometry: Listed application)
$640.46 View price
  • 100 μg
Delivery in 2 to 5 Business Days Shipping to: United States
ABIN7862850
SIRT1 antibody SIRT1 · Primary Antibody Human Mouse Monoclonal Clone PCRP-SIRT1-1E11
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
  • FACS (Flow Cytometry: Listed application)
$640.46 View price
  • 100 μg
  • 20 μg
Delivery in 2 to 5 Business Days Shipping to: United States
ABIN7220712
SIRT1 antibody (pSer47) SIRT1 · Primary Antibody Human, Mouse Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
$338.03 View price
  • 100 μL
  • 30 μL
  • 200 μL
Delivery in 12 to 16 Business Days Shipping to: United States
ABIN1935171
SIRT1 antibody (C-Term) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IP (Immunoprecipitation: Listed application)
  • PLA (Proximity Ligation Assay: Listed application)
$496.47 View price
  • 2 μg
  • 20 μg
Delivery in 11 to 15 Business Days Shipping to: United States
Primary Antibody
  • IF (cc) (Immunofluorescence (Cultured Cells): Validation image available)
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): Listed application)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
unconjugated
Protein Type
Recombinant Antibody
Isotype
IgG
Binding Specificity
pThr530
Catalog No. ABIN5557342
$490.77
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 8 to 12 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
Grade
Verified
Reactivity
Mouse
Host
Goat
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
Internal Region
Catalog No. ABIN185702
$488.25
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 1 to 3 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Validation image available)
  • ELISA (ELISA: Listed application)
Grade
Verified
Reactivity
Human
Host
Goat
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 577-590
Catalog No. ABIN625834
$488.25
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 1 to 3 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • IP (Immunoprecipitation: Listed application)
Reactivity
Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 238-482
Catalog No. ABIN7435919
$347.18
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
pSer47
Catalog No. ABIN7270323
$393.00
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 7 to 10 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Catalog No. ABIN1169086
$438.44
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 5 to 10 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
Reactivity
Rat
Host
Mouse
Clonality
Monoclonal
Clone
D4
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 238-482
Catalog No. ABIN7427144
$361.20
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
Tyr631
Catalog No. ABIN3186962
$413.63
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
Reactivity
Human, Mouse
Host
Mouse
Clonality
Monoclonal
Clone
AFfirm8967
Conjugate
unconjugated
Isotype
IgG1
Catalog No. ABIN8067573
$441.17
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 11 to 13 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • IP (Immunoprecipitation: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Clone
C2
Conjugate
unconjugated
Isotype
IgG2b kappa
Binding Specificity
AA 244-498
Catalog No. ABIN7426619
$340.17
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Primary Antibody
  • IHC (Immunohistochemistry: Validation image available)
  • WB (Western Blotting: Listed application)
  • FACS (Flow Cytometry: Listed application)
  • IF (cc) (Immunofluorescence (Cultured Cells): Listed application)
  • IF (p) (Immunofluorescence (Paraffin-embedded Sections): Listed application)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): Listed application)
  • IHC (fro) (Immunohistochemistry (Frozen Sections): Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 551-650
Catalog No. ABIN679028
$384.62
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 4 to 7 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Polyclonal
Conjugate
unconjugated
Binding Specificity
AA 456-555
Catalog No. ABIN565070
$350.04
Plus shipping costs $50.00
50 μL
Shipping to: United States
Delivery in 11 to 14 Business Days
Primary Antibody
  • IHC (Immunohistochemistry: Validation image available)
  • WB (Western Blotting: Listed application)
  • FACS (Flow Cytometry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
pSer27
Catalog No. ABIN746003
$384.62
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 4 to 7 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • IF (Immunofluorescence: Validation image available)
  • IHC (Immunohistochemistry: Validation image available)
  • IP (Immunoprecipitation: Listed application)
  • ChIP (Chromatin Immunoprecipitation: Listed application)
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Catalog No. ABIN7308334
$330.77
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 13 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • IHC (Immunohistochemistry: Validation image available)
  • IF (Immunofluorescence: Validation image available)
  • IP (Immunoprecipitation: Listed application)
  • IF/ICC (Immunofluorescence (fixed cells): Listed application)
  • ChIP (Chromatin Immunoprecipitation: Listed application)
Reactivity
Human, Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Catalog No. ABIN6006096
$472.66
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Human, Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 194-747
Catalog No. ABIN7571401
$317.38
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
  • FACS (Flow Cytometry: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Clone
PCRP-SIRT1-1E11
Conjugate
unconjugated
Isotype
IgG1
Catalog No. ABIN7126429
$640.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
  • FACS (Flow Cytometry: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Clone
PCRP-SIRT1-1E11
Conjugate
unconjugated
Isotype
IgG1
Catalog No. ABIN7862850
$640.46
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 5 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
pSer47
Catalog No. ABIN7220712
$338.03
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 12 to 16 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IP (Immunoprecipitation: Listed application)
  • PLA (Proximity Ligation Assay: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 700-747, C-Term
Catalog No. ABIN1935171
$496.47
Plus shipping costs $50.00
2 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days

Latest Publications for our SIRT1 Antibodies

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Zeng, Hu, He, Wang, Li, Xiong, Ye: "Hypothermic machine perfusion ameliorates inflammation during ischemia‑reperfusion injury via sirtuin‑1‑mediated deacetylation of nuclear factor‑κB p65 in rat livers donated after circulatory death." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8649-8656, (2018) (PubMed).

Zhang, Zhang, Guo, Zeng, Wu, Liu, He, Wang, Huang, Chen: "Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4082102, (2018) (PubMed).

Aliases for SIRT1 Antibodies

sirtuin 1 (SIRT1) Antibodies
sirtuin 1 (SRT1) Antibodies
sirtuin 1 (Sirt1) Antibodies
sirtuin 1 L homeolog (sirt1.L) Antibodies
AA673258 Antibodies
Sir2 Antibodies
SIR2 Antibodies
Sir2a Antibodies
Sir2alpha Antibodies
SIR2L1 Antibodies
sir2l1 Antibodies
sirtuin Antibodies
sirtuin 1 Antibodies
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