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SIRT1 Antibodies

(Sirtuin 1 (SIRT1))

SIRT1 (Sirtuin 1) is a protein that plays a role in regulating metabolism and has been implicated in the development and progression of obesity. Several studies have investigated the potential of targeting SIRT1 as a therapeutic strategy for obesity.

Research has shown that SIRT1 is involved in the regulation of nutrient sensing and can modulate lipid and glucose metabolism. It has been found to protect against high-fat diet-induced metabolic damage and hepatic lipid accumulation. SIRT1 has also been shown to promote lipid metabolism and mitochondrial function, which are important processes in adipogenesis and obesity.

In addition, SIRT1 has been found to counteract aging- and obesity-related diseases by deacetylating many proteins. It has been suggested that targeting SIRT1 activity in the brain may show promise for the treatment of obesity and associated metabolic disorders.

SIRT1 antibodies are essential research tools for better understanding the role of SIRT1 in in regulating metabolism, lipid metabolism, and mitochondrial function.

Active filters:

  • Target: SIRT1
  • Primary
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN2744364
SIRT1 antibody (AA 686-721) SIRT1 · Primary Antibody Mouse Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
$643.13 View price
  • 400 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN214826
SIRT1 antibody (AA 551-599) SIRT1 · Primary Antibody Human Mouse Monoclonal
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IP (Immunoprecipitation: Listed application)
$1,314.87 View price
  • 150 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN6780115
SIRT1 antibody (AA 244-498) SIRT1 · Primary Antibody Human Mouse Monoclonal
  • WB (Western Blotting: Listed application)
$525.80 View price
  • 100 μL
  • 1 mL
  • 5 mL
  • 200 μL
  • 500 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN2571309
SIRT1 antibody (AA 244-498) (FITC) SIRT1 · Primary Antibody Human Mouse Monoclonal
  • WB (Western Blotting: Listed application)
$635.80 View price
  • 200 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN2571313
SIRT1 antibody (AA 456-555) SIRT1 · Primary Antibody Human Mouse Monoclonal
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
$1,111.00 View price
  • 100 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN2571304
SIRT1 antibody (AA 244-498) (Biotin) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
$533.13 View price
  • 100 μL
  • 1 mL
  • 200 μL
  • 500 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN2571307
SIRT1 antibody (AA 244-498) (FITC) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
$575.67 View price
  • 100 μL
  • 1 mL
  • 200 μL
  • 500 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN2571306
SIRT1 antibody (AA 244-498) (Biotin) SIRT1 · Primary Antibody Human Mouse Monoclonal
  • WB (Western Blotting: Listed application)
$613.80 View price
  • 200 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN2571305
SIRT1 antibody (AA 236-490) (Biotin) SIRT1 · Primary Antibody Mouse Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
$536.07 View price
  • 100 μL
  • 1 mL
  • 200 μL
  • 500 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN6991343
SIRT1 antibody (N-Term) SIRT1 · Primary Antibody Human, Mouse, Rat Chicken Polyclonal
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
$577.50 View price
  • 100 μg
  • 20 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN6265090
SIRT1 antibody (N-Term) SIRT1 · Primary Antibody Human, Mouse Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
$441.17 View price
  • 100 μL
  • 200 μL
Delivery in 11 to 13 Business Days Shipping to: United States
ABIN6256350
SIRT1 antibody (pSer47) SIRT1 · Primary Antibody Human, Mouse Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
$441.17 View price
  • 100 μL
  • 200 μL
Delivery in 11 to 13 Business Days Shipping to: United States
ABIN7697662
SIRT1 antibody (Biotin) SIRT1 · Primary Antibody Mouse Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
$477.38 View price
  • 200 μL
  • 1 mL
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7699991
SIRT1 antibody (FITC) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
$571.52 View price
  • 200 μL
  • 1 mL
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7516460
Recombinant SIRT1 antibody SIRT1 · Primary Antibody Mouse Rabbit Monoclonal Clone R06-4K9
  • WB (Western Blotting: Listed application)
$617.04 View price
  • 100 μL
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7160853
SIRT1 antibody (AA 2-747) (FITC) SIRT1 · Primary Antibody Human Rabbit Polyclonal
$351.92 View price
  • 100 μg
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7160852
SIRT1 antibody (AA 2-747) (Biotin) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • ELISA (ELISA: Listed application)
$351.92 View price
  • 100 μg
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7160854
SIRT1 antibody (AA 2-747) (HRP) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • ELISA (ELISA: Listed application)
$351.92 View price
  • 100 μg
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7828566
Recombinant SIRT1 antibody (pSer47) SIRT1 · Primary Antibody Human Rabbit Monoclonal Clone A810
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
$351.92 View price
  • 50 μL
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7828565
Recombinant SIRT1 antibody (pSer27) SIRT1 · Primary Antibody Human Rabbit Monoclonal Clone A812
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
$351.92 View price
  • 50 μL
Delivery in 11 to 15 Business Days Shipping to: United States
Primary Antibody
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Binding Specificity
AA 686-721
Catalog No. ABIN2744364
$643.13
Plus shipping costs $50.00
400 μL
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IP (Immunoprecipitation: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
unconjugated
Isotype
IgG1
Binding Specificity
AA 551-599
Catalog No. ABIN214826
$1,314.87
Plus shipping costs $50.00
150 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 244-498
Catalog No. ABIN6780115
$525.80
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
FITC
Isotype
IgG
Binding Specificity
AA 244-498
Catalog No. ABIN2571309
$635.80
Plus shipping costs $50.00
200 μL
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
unconjugated
Isotype
IgG1 kappa
Binding Specificity
AA 456-555
Catalog No. ABIN2571313
$1,111.00
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Isotype
IgG
Binding Specificity
AA 244-498
Catalog No. ABIN2571304
$533.13
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
FITC
Isotype
IgG
Binding Specificity
AA 244-498
Catalog No. ABIN2571307
$575.67
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
Biotin
Isotype
IgG
Binding Specificity
AA 244-498
Catalog No. ABIN2571306
$613.80
Plus shipping costs $50.00
200 μL
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Isotype
IgG
Binding Specificity
AA 236-490
Catalog No. ABIN2571305
$536.07
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
Reactivity
Human, Mouse, Rat
Host
Chicken
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgY
Binding Specificity
N-Term
Catalog No. ABIN6991343
$577.50
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 4 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
N-Term
Catalog No. ABIN6265090
$441.17
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 11 to 13 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
pSer47
Catalog No. ABIN6256350
$441.17
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 11 to 13 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Isotype
IgG
Catalog No. ABIN7697662
$477.38
Plus shipping costs $50.00
200 μL (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
FITC
Isotype
IgG
Catalog No. ABIN7699991
$571.52
Plus shipping costs $50.00
200 μL (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Mouse
Host
Rabbit
Clonality
Monoclonal
Clone
R06-4K9
Conjugate
unconjugated
Protein Type
Recombinant Antibody
Isotype
IgG
Catalog No. ABIN7516460
$617.04
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 11 to 14 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
FITC
Isotype
IgG
Binding Specificity
AA 2-747
Catalog No. ABIN7160853
$351.92
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Primary Antibody
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Isotype
IgG
Binding Specificity
AA 2-747
Catalog No. ABIN7160852
$351.92
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Primary Antibody
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
HRP
Isotype
IgG
Binding Specificity
AA 2-747
Catalog No. ABIN7160854
$351.92
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Clone
A810
Conjugate
unconjugated
Protein Type
Recombinant Antibody
Isotype
IgG, kappa
Binding Specificity
pSer47
Catalog No. ABIN7828566
$351.92
Plus shipping costs $50.00
50 μL
Shipping to: United States
Delivery in 11 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Clone
A812
Conjugate
unconjugated
Protein Type
Recombinant Antibody
Isotype
IgG, kappa
Binding Specificity
pSer27
Catalog No. ABIN7828565
$351.92
Plus shipping costs $50.00
50 μL
Shipping to: United States
Delivery in 11 to 15 Business Days

Latest Publications for our SIRT1 Antibodies

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Zeng, Hu, He, Wang, Li, Xiong, Ye: "Hypothermic machine perfusion ameliorates inflammation during ischemia‑reperfusion injury via sirtuin‑1‑mediated deacetylation of nuclear factor‑κB p65 in rat livers donated after circulatory death." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8649-8656, (2018) (PubMed).

Zhang, Zhang, Guo, Zeng, Wu, Liu, He, Wang, Huang, Chen: "Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4082102, (2018) (PubMed).

Aliases for SIRT1 Antibodies

sirtuin 1 (SIRT1) Antibodies
sirtuin 1 (SRT1) Antibodies
sirtuin 1 (Sirt1) Antibodies
sirtuin 1 L homeolog (sirt1.L) Antibodies
AA673258 Antibodies
Sir2 Antibodies
SIR2 Antibodies
Sir2a Antibodies
Sir2alpha Antibodies
SIR2L1 Antibodies
sir2l1 Antibodies
sirtuin Antibodies
sirtuin 1 Antibodies
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