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SIRT1 Antibodies

(Sirtuin 1 (SIRT1))

SIRT1 (Sirtuin 1) is a protein that plays a role in regulating metabolism and has been implicated in the development and progression of obesity. Several studies have investigated the potential of targeting SIRT1 as a therapeutic strategy for obesity.

Research has shown that SIRT1 is involved in the regulation of nutrient sensing and can modulate lipid and glucose metabolism. It has been found to protect against high-fat diet-induced metabolic damage and hepatic lipid accumulation. SIRT1 has also been shown to promote lipid metabolism and mitochondrial function, which are important processes in adipogenesis and obesity.

In addition, SIRT1 has been found to counteract aging- and obesity-related diseases by deacetylating many proteins. It has been suggested that targeting SIRT1 activity in the brain may show promise for the treatment of obesity and associated metabolic disorders.

SIRT1 antibodies are essential research tools for better understanding the role of SIRT1 in in regulating metabolism, lipid metabolism, and mitochondrial function.

Active filters:

  • Target: SIRT1
  • Primary
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN6832285
SIRT1 antibody (pThr530) (Alexa Fluor 594) SIRT1 · Primary Antibody Human Rabbit Monoclonal Clone JJ206-6
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6832287
SIRT1 antibody (pSer47) (Alexa Fluor 594) SIRT1 · Primary Antibody Human Rabbit Polyclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6832282
SIRT1 antibody (Alexa Fluor 594) SIRT1 · Primary Antibody Human, Mouse, Rat Rabbit Polyclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6832283
Recombinant SIRT1 antibody (Alexa Fluor 594) SIRT1 · Primary Antibody Human Rabbit Monoclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6904662
Recombinant SIRT1 antibody (Alexa Fluor 680) SIRT1 · Primary Antibody Human Rabbit Monoclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN7844349
SIRT1 antibody SIRT1 · Primary Antibody Human Mouse Monoclonal
  • WB (Western Blotting: Listed application)
  • IP (Immunoprecipitation: Listed application)
$480.77 View price
  • 200 μL
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN7844350
SIRT1 antibody SIRT1 · Primary Antibody Human, Mouse Mouse Monoclonal
  • WB (Western Blotting: Listed application)
$480.77 View price
  • 200 μL
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN6856472
Recombinant SIRT1 antibody (Alexa Fluor 750) SIRT1 · Primary Antibody Human Rabbit Monoclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6816220
Recombinant SIRT1 antibody (Alexa Fluor 488) SIRT1 · Primary Antibody Human Rabbit Monoclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6872536
Recombinant SIRT1 antibody (Biotin) SIRT1 · Primary Antibody Human Rabbit Monoclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6915213
Recombinant SIRT1 antibody (Alexa Fluor 647) SIRT1 · Primary Antibody Human Rabbit Monoclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6888599
Recombinant SIRT1 antibody (Alexa Fluor 555) SIRT1 · Primary Antibody Human Rabbit Monoclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN5566470
SIRT1 antibody (AA 254-495) (PerCP) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • FACS (Flow Cytometry: Listed application)
$557.85 View price
  • 150 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN5566469
SIRT1 antibody (AA 254-495) (FITC) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • FACS (Flow Cytometry: Listed application)
$507.38 View price
  • 150 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN5566468
SIRT1 antibody (AA 254-495) (Biotin) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • EIA (Enzyme Immunoassay: Listed application)
  • RIA (Radioimmunoassay: Listed application)
$437.23 View price
  • 150 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN5566466
SIRT1 antibody (AA 254-495) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • EIA (Enzyme Immunoassay: Listed application)
  • RIA (Radioimmunoassay: Listed application)
$310.46 View price
  • 150 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN5566467
SIRT1 antibody (AA 254-495) (APC) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • FACS (Flow Cytometry: Listed application)
$507.38 View price
  • 150 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN5566471
SIRT1 antibody (AA 254-495) (PE) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • FACS (Flow Cytometry: Listed application)
$507.38 View price
  • 150 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN7847796
Recombinant SIRT1 antibody SIRT1 · Primary Antibody Human Rabbit Monoclonal
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
  • IP (Immunoprecipitation: Listed application)
$480.77 View price
  • 200 μL
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN2747513
SIRT1 antibody (AA 25-75) SIRT1 · Primary Antibody Human, Mouse, Rat, Monkey, Chicken Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
  • IP (Immunoprecipitation: Listed application)
$449.62 View price
  • 100 μg
  • 250 μg
Delivery in 1 to 3 Business Days Shipping to: United States
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Clone
JJ206-6
Conjugate
Alexa Fluor 594
Binding Specificity
pThr530
Catalog No. ABIN6832285
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Alexa Fluor 594
Binding Specificity
pSer47
Catalog No. ABIN6832287
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human, Mouse, Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
Alexa Fluor 594
Catalog No. ABIN6832282
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Alexa Fluor 594
Protein Type
Recombinant Antibody
Catalog No. ABIN6832283
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Alexa Fluor 680
Protein Type
Recombinant Antibody
Catalog No. ABIN6904662
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IP (Immunoprecipitation: Listed application)
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
unconjugated
Catalog No. ABIN7844349
$480.77
Plus shipping costs $50.00
200 μL
Shipping to: United States
Delivery in 4 to 5 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
Reactivity
Human, Mouse
Host
Mouse
Clonality
Monoclonal
Conjugate
unconjugated
Catalog No. ABIN7844350
$480.77
Plus shipping costs $50.00
200 μL
Shipping to: United States
Delivery in 4 to 5 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Alexa Fluor 750
Protein Type
Recombinant Antibody
Catalog No. ABIN6856472
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Alexa Fluor 488
Protein Type
Recombinant Antibody
Catalog No. ABIN6816220
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Biotin
Protein Type
Recombinant Antibody
Catalog No. ABIN6872536
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Alexa Fluor 647
Protein Type
Recombinant Antibody
Catalog No. ABIN6915213
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Alexa Fluor 555
Protein Type
Recombinant Antibody
Catalog No. ABIN6888599
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
  • FACS (Flow Cytometry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
PerCP
Binding Specificity
AA 254-495
Catalog No. ABIN5566470
$557.85
Plus shipping costs $50.00
150 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Primary Antibody
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • FACS (Flow Cytometry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
FITC
Binding Specificity
AA 254-495
Catalog No. ABIN5566469
$507.38
Plus shipping costs $50.00
150 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Primary Antibody
  • EIA (Enzyme Immunoassay: Listed application)
  • RIA (Radioimmunoassay: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Binding Specificity
AA 254-495
Catalog No. ABIN5566468
$437.23
Plus shipping costs $50.00
150 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Primary Antibody
  • EIA (Enzyme Immunoassay: Listed application)
  • RIA (Radioimmunoassay: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Binding Specificity
AA 254-495
Catalog No. ABIN5566466
$310.46
Plus shipping costs $50.00
150 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Primary Antibody
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • FACS (Flow Cytometry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
APC
Binding Specificity
AA 254-495
Catalog No. ABIN5566467
$507.38
Plus shipping costs $50.00
150 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Primary Antibody
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • FACS (Flow Cytometry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
PE
Binding Specificity
AA 254-495
Catalog No. ABIN5566471
$507.38
Plus shipping costs $50.00
150 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IF (Immunofluorescence: Listed application)
  • IP (Immunoprecipitation: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
unconjugated
Protein Type
Recombinant Antibody
Catalog No. ABIN7847796
$480.77
Plus shipping costs $50.00
200 μL
Shipping to: United States
Delivery in 4 to 5 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
  • IP (Immunoprecipitation: Listed application)
Reactivity
Human, Mouse, Rat, Monkey, Chicken
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 25-75
Catalog No. ABIN2747513
$449.62
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 1 to 3 Business Days

Latest Publications for our SIRT1 Antibodies

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Zeng, Hu, He, Wang, Li, Xiong, Ye: "Hypothermic machine perfusion ameliorates inflammation during ischemia‑reperfusion injury via sirtuin‑1‑mediated deacetylation of nuclear factor‑κB p65 in rat livers donated after circulatory death." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8649-8656, (2018) (PubMed).

Zhang, Zhang, Guo, Zeng, Wu, Liu, He, Wang, Huang, Chen: "Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4082102, (2018) (PubMed).

Aliases for SIRT1 Antibodies

sirtuin 1 (SIRT1) Antibodies
sirtuin 1 (SRT1) Antibodies
sirtuin 1 (Sirt1) Antibodies
sirtuin 1 L homeolog (sirt1.L) Antibodies
AA673258 Antibodies
Sir2 Antibodies
SIR2 Antibodies
Sir2a Antibodies
Sir2alpha Antibodies
SIR2L1 Antibodies
sir2l1 Antibodies
sirtuin Antibodies
sirtuin 1 Antibodies
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