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SIRT1 Antibodies

(Sirtuin 1 (SIRT1))

SIRT1 (Sirtuin 1) is a protein that plays a role in regulating metabolism and has been implicated in the development and progression of obesity. Several studies have investigated the potential of targeting SIRT1 as a therapeutic strategy for obesity.

Research has shown that SIRT1 is involved in the regulation of nutrient sensing and can modulate lipid and glucose metabolism. It has been found to protect against high-fat diet-induced metabolic damage and hepatic lipid accumulation. SIRT1 has also been shown to promote lipid metabolism and mitochondrial function, which are important processes in adipogenesis and obesity.

In addition, SIRT1 has been found to counteract aging- and obesity-related diseases by deacetylating many proteins. It has been suggested that targeting SIRT1 activity in the brain may show promise for the treatment of obesity and associated metabolic disorders.

SIRT1 antibodies are essential research tools for better understanding the role of SIRT1 in in regulating metabolism, lipid metabolism, and mitochondrial function.

Active filters:

  • Target: SIRT1
  • Primary
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN5706832
Rockland Original
SIRT1 antibody (C-Term) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
$509.00 View price
  • 100 μg
Delivery in 1 to 3 Business Days Shipping to: United States
ABIN5958340
SIRT1 antibody (Ser47) SIRT1 · Primary Antibody Human, Mouse, Rat Rabbit Polyclonal
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): Listed application)
$480.43 View price
  • 200 μL
  • 120 μL
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7603404
SIRT1 antibody (pThr530) SIRT1 · Primary Antibody Human Rabbit Monoclonal Clone HAI-19
  • WB (Western Blotting: Validation image available)
$390.00 View price
  • 100 μL
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN7627154
SIRT1 antibody (AA 1-490) SIRT1 · Primary Antibody Rat Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • IP (Immunoprecipitation: Listed application)
$466.15 View price
  • 100 μL
  • 1 mL
  • 200 μL
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN7812866
SIRT1 antibody SIRT1 · Primary Antibody Human, Mouse, Rat Rabbit Polyclonal
$280.50 View price
  • 100 μg
Delivery in 7 to 10 Business Days Shipping to: United States
ABIN8037750
SIRT1 antibody (AA 112-311) (Biotin) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
$590.00 View price
  • 100 μg
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN8037761
SIRT1 antibody (AA 142-533) (Biotin) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
$590.00 View price
  • 100 μg
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN8037767
SIRT1 antibody (AA 142-533) (HRP) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
$590.00 View price
  • 100 μg
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN8037756
SIRT1 antibody (AA 112-311) (HRP) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
$590.00 View price
  • 100 μg
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN8037771
SIRT1 antibody (AA 142-533) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
$390.00 View price
  • 100 μg
Delivery in 4 to 7 Business Days Shipping to: United States
ABIN6353143
SIRT1 antibody (Biotin) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF/ICC (Immunofluorescence (fixed cells): Listed application)
$565.06 View price
  • 200 μL
  • 1 mL
  • 10 μL
  • 50 μL
  • 100 μL
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN6354101
SIRT1 antibody (Biotin) SIRT1 · Primary Antibody Mouse Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF/ICC (Immunofluorescence (fixed cells): Listed application)
$580.46 View price
  • 200 μL
  • 1 mL
  • 10 μL
  • 50 μL
  • 100 μL
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN6081569
SIRT1 antibody (AA 2-747) (FITC) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • ELISA (ELISA: Listed application)
$580.46 View price
  • 100 μL
  • 20 μL
  • 50 μL
Delivery in 10 to 18 Business Days Shipping to: United States
ABIN7565978
SIRT1 antibody (C-Term) SIRT1 · Primary Antibody Human Rabbit Polyclonal
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
$125.00 View price
  • 25 μL
Delivery in 1 to 3 Business Days Shipping to: United States
ABIN6904664
SIRT1 antibody (pThr530) (Alexa Fluor 680) SIRT1 · Primary Antibody Human Rabbit Monoclonal Clone JJ206-6
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6904663
SIRT1 antibody (pSer47) (Alexa Fluor 680) SIRT1 · Primary Antibody Human Rabbit Monoclonal Clone SN06-40
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6904666
SIRT1 antibody (pSer47) (Alexa Fluor 680) SIRT1 · Primary Antibody Human Rabbit Polyclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6904661
SIRT1 antibody (Alexa Fluor 680) SIRT1 · Primary Antibody Human, Mouse, Rat Rabbit Polyclonal
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6888601
SIRT1 antibody (pThr530) (Alexa Fluor 555) SIRT1 · Primary Antibody Human Rabbit Monoclonal Clone JJ206-6
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
ABIN6888600
SIRT1 antibody (pSer47) (Alexa Fluor 555) SIRT1 · Primary Antibody Human Rabbit Monoclonal Clone SN06-40
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
$515.90 View price
  • 100 μL
Delivery in 6 to 9 Business Days Shipping to: United States
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
Supplier Product No.
Rockland 600-401-gw4
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
C-Term
Catalog No. ABIN5706832
$509.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 1 to 3 Business Days
Rockland Original
Primary Antibody
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): Listed application)
Reactivity
Human, Mouse, Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
Ser47
Catalog No. ABIN5958340
$480.43
Plus shipping costs $50.00
200 μL (More quantities available)
Shipping to: United States
Delivery in 12 to 15 Business Days
Primary Antibody
  • WB (Western Blotting: Validation image available)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Clone
HAI-19
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
pThr530
Catalog No. ABIN7603404
$390.00
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 4 to 7 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ICC (Immunocytochemistry: Listed application)
  • IP (Immunoprecipitation: Listed application)
Reactivity
Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Binding Specificity
AA 1-490
Catalog No. ABIN7627154
$466.15
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 2 to 4 Business Days
Primary Antibody
Reactivity
Human, Mouse, Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Catalog No. ABIN7812866
$280.50
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 7 to 10 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Isotype
IgG
Binding Specificity
AA 112-311
Catalog No. ABIN8037750
$590.00
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Isotype
IgG
Binding Specificity
AA 142-533
Catalog No. ABIN8037761
$590.00
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
HRP
Isotype
IgG
Binding Specificity
AA 142-533
Catalog No. ABIN8037767
$590.00
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
HRP
Isotype
IgG
Binding Specificity
AA 112-311
Catalog No. ABIN8037756
$590.00
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
Grade
Carrier-free
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Isotype
IgG
Binding Specificity
AA 142-533
Catalog No. ABIN8037771
$390.00
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF/ICC (Immunofluorescence (fixed cells): Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Isotype
IgG
Catalog No. ABIN6353143
$565.06
Plus shipping costs $50.00
200 μL (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF/ICC (Immunofluorescence (fixed cells): Listed application)
Reactivity
Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
Biotin
Isotype
IgG
Catalog No. ABIN6354101
$580.46
Plus shipping costs $50.00
200 μL (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Primary Antibody
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
FITC
Isotype
IgG
Binding Specificity
AA 2-747
Catalog No. ABIN6081569
$580.46
Plus shipping costs $50.00
100 μL (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
unconjugated
Binding Specificity
C-Term
Catalog No. ABIN7565978
$125.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
25 μL
Shipping to: United States
Delivery in 1 to 3 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Clone
JJ206-6
Conjugate
Alexa Fluor 680
Binding Specificity
pThr530
Catalog No. ABIN6904664
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Clone
SN06-40
Conjugate
Alexa Fluor 680
Binding Specificity
pSer47
Catalog No. ABIN6904663
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Alexa Fluor 680
Binding Specificity
pSer47
Catalog No. ABIN6904666
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
Reactivity
Human, Mouse, Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
Alexa Fluor 680
Catalog No. ABIN6904661
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Clone
JJ206-6
Conjugate
Alexa Fluor 555
Binding Specificity
pThr530
Catalog No. ABIN6888601
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
Primary Antibody
  • WB (Western Blotting: Listed application)
  • IHC (Immunohistochemistry: Listed application)
  • IF (Immunofluorescence: Listed application)
  • ICC (Immunocytochemistry: Listed application)
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Clone
SN06-40
Conjugate
Alexa Fluor 555
Binding Specificity
pSer47
Catalog No. ABIN6888600
$515.90
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 6 to 9 Business Days

Latest Publications for our SIRT1 Antibodies

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Zeng, Hu, He, Wang, Li, Xiong, Ye: "Hypothermic machine perfusion ameliorates inflammation during ischemia‑reperfusion injury via sirtuin‑1‑mediated deacetylation of nuclear factor‑κB p65 in rat livers donated after circulatory death." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8649-8656, (2018) (PubMed).

Zhang, Zhang, Guo, Zeng, Wu, Liu, He, Wang, Huang, Chen: "Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4082102, (2018) (PubMed).

Aliases for SIRT1 Antibodies

sirtuin 1 (SIRT1) Antibodies
sirtuin 1 (SRT1) Antibodies
sirtuin 1 (Sirt1) Antibodies
sirtuin 1 L homeolog (sirt1.L) Antibodies
AA673258 Antibodies
Sir2 Antibodies
SIR2 Antibodies
Sir2a Antibodies
Sir2alpha Antibodies
SIR2L1 Antibodies
sir2l1 Antibodies
sirtuin Antibodies
sirtuin 1 Antibodies
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