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SLAMF6 Products

(SLAM Family Member 6 (SLAMF6))

Categories

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010].

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Featured SLAMF6 Categories

SLAMF6 Antibodies

High quality antibodies with extensive validation data.

SLAMF6 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLAMF6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLAMF6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN7169782
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN530287
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (1)
Cat. No. ABIN7092959
Quantity 100 μg
Datasheet Datasheet

Recommended SLAMF6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884012
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384208
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730057
Quantity 96 tests
Datasheet Datasheet

Recommended SLAMF6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275622
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275620
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275626
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SLAMF6 products

Joas, Parrish, Gnanadurai, Lump, Stürzel, Parrish, Learn, Sauermann, Neumann, Rensing, Fuchs, Billingsley, Bosinger, Silvestri, Apetrei, Huot, Garcia-Tellez, Müller-Trutwin, Hotter, Sauter et al.: "Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity. ..." in: Nature communications, Vol. 9, Issue 1, pp. 1371, (2018) (PubMed).

Davis, Sowrirajan, Cogswell, Ward, Planelles, Barker: "CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells." in: AIDS research and human retroviruses, Vol. 33, Issue 2, pp. 93-100, (2017) (PubMed).

Kmiec, Iyer, Stürzel, Sauter, Hahn, Kirchhoff: "Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance." in: mBio, Vol. 7, Issue 4, (2016) (PubMed).

Sullivan, Jeha, Kang, Cheng, Rooney, Holladay, Bari, Schell, Tuggle, Pui, Leung: "NK cell genotype and phenotype at diagnosis of acute lymphoblastic leukemia correlate with postinduction residual disease." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 23, pp. 5986-94, (2014) (PubMed).

Proust, Bertoglio, Gesbert: "The adaptor protein SAP directly associates with CD3? chain and regulates T cell receptor signaling." in: PLoS ONE, Vol. 7, Issue 8, pp. e43200, (2012) (PubMed).

Hislop, Palendira, Leese, Arkwright, Rohrlich, Tangye, Gaspar, Lankester, Moretta, Rickinson: "Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets." in: Blood, Vol. 116, Issue 17, pp. 3249-57, (2010) (PubMed).

Cabezón, Sintes, Llinàs, Benitez-Ribas: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." in: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).

Matesanz-Isabel, Sintes, Llinàs, de Salort, Lázaro, Engel: "New B-cell CD molecules." in: Immunology letters, Vol. 134, Issue 2, pp. 104-12, (2010) (PubMed).

Brunetta, Fogli, Varchetta, Bozzo, Hudspeth, Marcenaro, Moretta, Mavilio: "The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia." in: Blood, Vol. 114, Issue 18, pp. 3822-30, (2009) (PubMed).

Banerjee, Feuer, Barker et al.: "Human T-cell leukemia virus type 1 (HTLV-1) p12I down-modulates ICAM-1 and -2 and reduces adherence of natural killer cells, thereby protecting HTLV-1-infected primary CD4+ T cells from autologous ..." in: Journal of virology, Vol. 81, Issue 18, pp. 9707-17, (2007) (PubMed).

Synonyms and alternative names related to SLAMF6

SLAM family member 6 (SLAMF6), SLAM family member 6 (Slamf6), CD352, KAL1, KAL1b, KALI, KALIb, Ly108, NTB-A, NTBA, RGD1561848, SF2000, SLAMF6

Protein level used designations for SLAMF6

  • SLAM family member 6
  • activating NK receptor
  • NK-T-B-antigen
  • NTBA receptor
  • natural killer-, T- and B-cell antigen
  • lymphocyte antigen 108
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