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SLC10A2 Products

(Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2))

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This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM)\; muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010].

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Featured SLC10A2 Categories

SLC10A2 Antibodies

High quality antibodies with extensive validation data.

SLC10A2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC10A2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, ELISA
Validations
  • (2)
  • (3)
Cat. No. ABIN755143
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7075648
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6260071
Quantity 100 μL
Datasheet Datasheet

Recommended SLC10A2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1330485
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3099586
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120902
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SLC10A2 products

Ding, Yang, Qu, Yang, Wang, Liu, Xia: "Bile acid promotes liver regeneration via farnesoid X receptor signaling pathways in rats." in: Molecular medicine reports, (2015) (PubMed).

Zhao, Zitzow, Ehresman, Chang, Butenhoff, Forster, Hagenbuch: "Na+/Taurocholate Cotransporting Polypeptide and Apical Sodium-Dependent Bile Acid Transporter Are Involved in the Disposition of Perfluoroalkyl Sulfonates in Humans and Rats." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 146, Issue 2, pp. 363-73, (2015) (PubMed).

Al-Hilal, Park, Alam, Chung, Park, Kim, Kwon, Kim, Kim, Byun: "Oligomeric bile acid-mediated oral delivery of low molecular weight heparin." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 175, pp. 17-24, (2014) (PubMed).

Wu, He, Wang, Xue, Ning, Zou, Ye, Li, Wang, Pang: "The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 11, pp. 1373-81, (2014) (PubMed).

Annaba, Sarwar, Kumar, Saksena, Turner, Dudeja, Gill, Alrefai: "Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 294, Issue 2, pp. G489-97, (2008) (PubMed).

Vargas, Nore, Berglof, Heinonen, Mattsson, Smith, Mohamed: "Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx." in: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9351-7, (2002) (PubMed).

Rajantie, Ekman, Iljin, Arighi, Gunji, Kaukonen, Palotie, Dewerchin, Carmeliet, Alitalo: "Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium." in: Molecular and cellular biology, Vol. 21, Issue 14, pp. 4647-55, (2001) (PubMed).

Kaukonen, Lahtinen, Laine, Alitalo, Palotie: "BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias." in: British journal of haematology, Vol. 94, Issue 3, pp. 455-60, (1996) (PubMed).

Synonyms and alternative names related to SLC10A2

solute carrier family 10 member 2 (SLC10A2), solute carrier family 10 (sodium/bile acid cotransporter), member 2 (slc10a2), solute carrier family 10 member 2 (Slc10a2), solute carrier family 10, member 2 (Slc10a2), ASBT, IBAT, ISBAT, ISBT, NTCP2, PBAM, zgc:63998

Protein level used designations for SLC10A2

  • solute carrier family 10 (sodium/bile acid cotransporter family), member 2
  • ileal sodium/bile acid cotransporter
  • ASBT
  • IBAT
  • ISBT
  • Na(+)-dependent ileal bile acid transporter
  • apical sodium-dependent bile acid transporter
  • ileal Na(+)/bile acid cotransporter
  • ileal sodium-dependent bile acid transporter
  • sodium/taurocholate cotransporting polypeptide, ileal
  • solute carrier family 10 member 2
  • sodium/taurocholate-cotransporting polypeptide, ileal
  • solute carrier family 10, member 2
  • ileal apical sodium-dependent bile acid transporter
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