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anti-Human MED15 Antibodies:
anti-Mouse (Murine) MED15 Antibodies:
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Human Monoclonal MED15 Primary Antibody for IF, ELISA - ABIN565638
Varelas, Sakuma, Samavarchi-Tehrani, Peerani, Rao, Dembowy, Yaffe, Zandstra, Wrana: TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. in Nature cell biology 2008
Show all 2 Pubmed References
Human Polyclonal MED15 Primary Antibody for ELISA, WB - ABIN449910
Thakur, Arthanari, Yang, Pan, Fan, Breger, Frueh, Gulshan, Li, Mylonakis, Struhl, Moye-Rowley, Cormack, Wagner, Näär: A nuclear receptor-like pathway regulating multidrug resistance in fungi. in Nature 2008
Human Polyclonal MED15 Primary Antibody for ICC, IF - ABIN4333404
Thiaville, Dudenhausen, Awad, Gjymishka, Zhong, Kilberg: Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex. in Nucleic acids research 2008
MED15 does seem to play a tumour promoting role in the progression and metastatic spread of renal cell carcinoma (show MOK Antibodies)
MED15 overexpression arises during androgen deprivation therapy via hyper-activation of PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway in prostate cancer cells.
MED15 as a potential biomarker for head and neck squamous cell carcinoma
MED15 is differentially expressed in tumor-free testis and testicular germ cell tumors
MED15 overexpression is a clonal event during head and neck squamous cell carcinoma progression.
these findings implicate MED15 in CRPC, and as MED15 is evolutionary conserved, it is likely to emerge as a lethal phenotype in other therapeutic-resistant diseases, and not restricted to our disease model.
MED15 and PUM1 (show PUM1 Antibodies) proteins with coiled-coil domains are potent enhancers of polyQ-mediated ataxin-1 (show ATXN1 Antibodies) protein misfolding and proteotoxicity in vitro and in vivo.
The data identify PC2 (show KRT6B Antibodies) as a novel PLAGL2 (show PLAGL2 Antibodies)-binding protein and important mediator of PLAGL2 (show PLAGL2 Antibodies) transactivation.
Methylation of TIG1 (show RARRES1 Antibodies) in prostatic neoplasms correlates with methylation of the retinoic acid receptor beta (show RARB Antibodies) gene.
Limited role of exon 7 PCQAP polymorphisms in the pathogenesis of schizophrenia.
The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Two transcript variants encoding different isoforms have been found for this gene.
, mediator complex subunit 15
, PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein
, mediator of RNA polymerase II transcription subunit 15
, CTG repeat protein 7a
, PC2 glutamine/Q-rich-associated protein
, PC2-glutamine-rich-associated protein
, TPA inducible gene-1
, TPA inducible protein
, TPA-inducible gene 1 protein
, activator-recruited cofactor 105 kDa component
, activator-recruited cofactor, 105-kD
, positive cofactor 2 glutamine/Q-rich-associated protein
, positive cofactor 2, glutamine/Q-rich-associated protein
, trinucleotide repeat containing 7
, trinucleotide repeat-containing gene 7 protein
, positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein