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Chromosome mapping of 3 proteins (CRSP9, ETF1 and TMEM59) in swine
In the absence of Med7, the ribosomal regulon is de-repressed, suggesting Med7 is involved in central aspects of growth control.
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.
CRSP complex subunit 9
, RNA polymerase transcriptional regulation mediator subunit 7 homolog
, activator-recruited cofactor 34 kDa component
, cofactor required for Sp1 transcriptional activation subunit 9
, cofactor required for Sp1 transcriptional activation, subunit 9 (33kD)
, cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa
, mediator of RNA polymerase II transcription subunit 7
, transcriptional coactivator CRSP33
, CRSP complex subunit 9-A
, cofactor required for Sp1 transcriptional activation subunit 9-A
, mediator complex subunit 7-A
, mediator of RNA polymerase II transcription subunit 7-A
, mediator of RNA polymerase II transcription subunit 7-like
, hypothetical protein
, Mediator complex subunit 7