anti-Rat (Rattus) NMDAR2A antibody for Immunoprecipitation

Recommended NMDAR2A Antibody

Antigen
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
  • NMDAR2A
  • nr2a
  • GRIN2A
  • EPND
  • GluN2A
  • NR2A
  • glutamate ionotropic receptor NMDA type subunit 2A
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog
  • glutamate receptor ionotropic, NMDA 2A
  • glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • GRIN2A
  • grin2a.L
  • LOC100438553
  • Grin2a
Epitope
C-Term
87
28
24
19
15
10
9
8
8
8
8
7
5
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Rat (Rattus)
238
187
184
7
4
3
2
2
1
1
1
Host
Rabbit
195
105
1
Clonality
Polyclonal
Conjugate
This NMDAR2A antibody is un-conjugated
20
16
14
11
9
9
7
6
6
6
6
6
6
5
5
5
5
5
5
5
5
5
3
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
229
172
62
59
53
33
26
26
20
15
3
3
2
1
Options

Available images

Catalog No. ABIN361396
$ 508.20
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
19.701527 ABIN6254088 IHC IP WB Rabbit C-Term Polyclonal 0
13.701527 ABIN1690078 IP Magnetic Particles Rabbit Polyclonal 0
13.701527 ABIN1690426 IP Sepharose Rabbit Polyclonal 0
10 ABIN5551596 IHC (fro) IP WB Rabbit IgG C-Term Polyclonal 6
1 ABIN1493384 IP Sepharose Rabbit AA 1411-1427 Polyclonal 0
1 ABIN1493383 IP Magnetic Particles Rabbit AA 1411-1427 Polyclonal 0
1 ABIN211363 IP WB Rabbit IgG AA 1265-1464 Polyclonal 0
1 ABIN2277272 IP IHC WB Rabbit IgG AA 1253-1391 Polyclonal 0
1 ABIN5541473 IP WB Rabbit Ig Fraction C-Term Polyclonal 0
-13.206343 ABIN4340158 IHC IHC (p) IP WB Rabbit C-Term Polyclonal 0

General

Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
Epitope C-Term
(87), (28), (24), (19), (15), (10), (9), (8), (8), (8), (8), (7), (5), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(238), (187), (184), (7), (4), (3), (2), (2), (1), (1), (1)
Host Rabbit
(195), (105), (1)
Clonality
Polyclonal
Conjugate This NMDAR2A antibody is un-conjugated
(20), (16), (14), (11), (9), (9), (7), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
(229), (172), (62), (59), (53), (33), (26), (26), (20), (15), (3), (3), (2), (1)
Supplier

Product Details anti-NMDAR2A Antibody

Target Details NMDAR2A Application Details Handling Images
Specificity Specific for the ~180k NR2A subunit of the NMDA receptor. Recognizes human, mouse and rat forms of the NR2A subunit of NMDAR. No reactivity towards the NR2B and NR2C subunits. Immunolabeling is blocked by pre-adsorption of antibody with the fusion protein used to generate the antibody.
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification Antigen Affinity Purified from Pooled Serum
Immunogen Fusion protein from the C-terminal region of the NR2A subunit
Plasmids, Primers & others

Target Details NMDAR2A

Product Details anti-NMDAR2A Antibody Application Details Handling Images back to top
Antigen
Alternative Name GRIN2A (GRIN2A Antibody Abstract)
Background The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002, Wenthold et al., 2003, Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989, Alvestad et al., 2003, Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Anti-NMDA Receptor, NR2A Subunit Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~180k NR2A subunit of the NMDA receptor.
Molecular Weight '180 kDa
Gene ID 24409
UniProt Q00959
Pathways Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Handling Images back to top
Application Notes Recommended Dilution: WB: 1:1000 IHC (frozen sections, unpublished observations): 1:1000 to 1:2000 IP: 3 µl per 200 µg lysate Quality Control: Western blots performed on each lot.
Restrictions For Research Use only

Handling

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Images back to top
Format Lyophilized
Buffer Lyophilized
Storage -20 °C

Images

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (C-Term) antibody (ABIN361396) Western blots of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeli...
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (C-Term) antibody (ABIN361396) Western blot of 10 µg of rat hippocampal lysate showing specific immunolabeling of th...
Immunostaining (ISt) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (C-Term) antibody (ABIN361396) Immunostaining of rabbit retina showing NR2A in the rod and cone photoreceptors in the