anti-Rat (Rattus) CBL antibody for Flow Cytometry
Recommended CBL Antibody (supplied by: Log in to see )
- Antigen
-
Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies
show synonyms for this antigen- 4732447J05Rik
- Cbl-2
- c-Cbl
- cbl
- C-CBL
- CBL2
- FRA11B
- NSLL
- RNF55
- c-cbl-like
- RGD1561386
- Casitas B-lineage lymphoma
- Cbl proto-oncogene
- Cbl
- CBL
- Reactivity
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Human, Mouse (Murine), Rat (Rattus)
Alternatives - Host
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Mouse
Alternatives - Clonality
- Conjugate
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This CBL antibody is un-conjugated
Alternatives - Application
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Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Alternatives - Options
- Supplier
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- Supplier Product No.
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| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 13.403709 | ABIN4288401 | ELISA FACS ICC IF IHC WB | Mouse | IgG1 | Log in to see | 3B12 | 0 | |||
| 13.403709 | ABIN1845278 | ELISA FACS IF/ICC IHC WB | Mouse | IgG1 | Log in to see | 0 | ||||
| 1 | ABIN2590840 | ELISA FACS IF IHC IHC (p) WB | Mouse | IgG1 | Log in to see | 3B12 | 0 | |||
| 1 | ABIN4880224 | ELISA FACS ICC IHC WB | Mouse | IgG1 | Log in to see | 3B12 | 0 | |||
| 1 | ABIN2665478 | FACS | Rabbit | Log in to see | Polyclonal | 1 | ||||
| 1 | ABIN4901147 | ELISA FACS IF IHC WB | Mouse | IgG1 | Log in to see | 3B12 | 0 |
General |
|
|---|---|
| Antigen | Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibodies |
| Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
| Host | Mouse Alternatives |
| Clonality (Clone) | |
| Conjugate | This CBL antibody is un-conjugated Alternatives |
| Application |
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Alternatives
|
|
3 references available |
| Supplier | Log in to see |
Product Details anti-CBL AntibodyTarget Details CBL Application Details Handling References for anti-CBL antibody (ABIN968993) Images |
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| Purification | Ascites |
| Immunogen | Purified recombinant fragment of human C-CBL expressed in E. Coli. |
| Clone | 3B12 |
| Isotype | IgG1 |
| Plasmids, Primers & others | |
Target Details CBLProduct Details anti-CBL Antibody Application Details Handling References for anti-CBL antibody (ABIN968993) Images back to top |
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| Antigen | |
| Alternative Name | C-CBL (CBL Antibody Abstract) |
| Background | The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. |
| Molecular Weight | 120 kDa |
| Gene ID | 867 |
| HGNC | 867 |
| Pathways | TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals |
Application DetailsProduct Details anti-CBL Antibody Target Details CBL Handling References for anti-CBL antibody (ABIN968993) Images back to top |
|
| Application Notes | ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400 |
| Restrictions | For Research Use only |
HandlingProduct Details anti-CBL Antibody Target Details CBL Application Details References for anti-CBL antibody (ABIN968993) Images back to top |
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| Format | Liquid |
| Buffer | Ascitic fluid containing 0.03 % sodium azide. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Storage | 4 °C,-20 °C |
| Storage Comment | 4°C, -20°C for long term storage |
References for anti-CBL antibody (ABIN968993)Product Details anti-CBL Antibody Target Details CBL Application Details Handling Images back to top |
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| Product cited in: |
Sproul, Xu, Wilhelm, Gire, Greene: "Cbl negatively regulates JNK activation and cell death." in: Cell research, Vol. 19, Issue 8, pp. 950-61, 2009 Sanada, Suzuki, Shih, Otsu, Kato, Yamazaki, Tamura, Honda, Sakata-Yanagimoto, Kumano, Oda, Yamagata, Takita, Gotoh, Nakazaki, Kawamata, Onodera, Nobuyoshi, Hayashi, Harada, Kurokawa, Chiba, Mori et al.: "Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. ..." in: Nature, Vol. 460, Issue 7257, pp. 904-8, 2009 Loh, Sakai, Flotho, Kang, Fliegauf, Archambeault, Mullighan, Chen, Bergstraesser, Bueso-Ramos, Emanuel, Hasle, Issa, van den Heuvel-Eibrink, Locatelli, Stary, Trebo, Wlodarski, Zecca, Shannon et al.: "Mutations in CBL occur frequently in juvenile myelomonocytic leukemia. ..." in: Blood, Vol. 114, Issue 9, pp. 1859-63, 2009 |
ImagesProduct Details anti-CBL Antibody Target Details CBL Application Details Handling References for anti-CBL antibody (ABIN968993) back to top |
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| Supplier Images |
Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Figure 2: Flow cytometric analysis of MCF-7 cells using C-CBL mouse mAb (blue) and ne...
Figure 3: Immunofluorescence analysis of Hela cells using C-CBL mouse mAb (green) . B...
Figure 4: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues us...
Figure 5: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues us...
Figure 6: Western blot analysis using C-CBL mouse mAb against RAJI (1), RAW264.7 (2),...
Figure 7: Western blot analysis using C-CBL mAb against human C-CBL (AA: 684-865) rec...
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