anti-Rat (Rattus) CD86 antibody for Intracellular Flow Cytometry

Recommended CD86 Antibody (supplied by: Log in to see )

Antigen
CD86 Molecule (CD86) Antibodies
  • B7-2
  • B7
  • B7.2
  • B70
  • CLS1
  • Cd28l2
  • ETC-1
  • Ly-58
  • Ly58
  • MB7
  • MB7-2
  • TS/A-2
  • CD28LG2
  • LAB72
  • CD86 molecule
  • CD86 antigen
  • CD86
  • Cd86
Reactivity
Rat (Rattus)
462
413
180
10
6
3
2
2
1
1
Host
Mouse
378
311
110
1
Clonality
Monoclonal
Conjugate
This CD86 antibody is conjugated to FITC
98
96
55
49
21
15
13
11
10
9
9
8
7
6
5
5
4
4
4
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Intracellular Flow Cytometry (ICFC)
615
250
180
176
133
96
88
69
55
54
44
16
13
13
11
11
8
2
2
2
2
1
1
1
1
1
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Catalog No. ABIN2661836
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN2661142 ICFC Biotin Mouse IgG1 kappa Log in to see 24F 5

General

Antigen CD86 Molecule (CD86) Antibodies
Reactivity Rat (Rattus)
(462), (413), (180), (10), (6), (3), (2), (2), (1), (1)
Host Mouse
(378), (311), (110), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD86 antibody is conjugated to FITC
(98), (96), (55), (49), (21), (15), (13), (11), (10), (9), (9), (8), (7), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Intracellular Flow Cytometry (ICFC)
(615), (250), (180), (176), (133), (96), (88), (69), (55), (54), (44), (16), (13), (13), (11), (11), (8), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-CD86 Antibody

Target Details CD86 Application Details Handling References for anti-CD86 antibody (ABIN2661836) Images
Purification The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone 24F
Isotype IgG1 kappa
Plasmids, Primers & others

Target Details CD86

Product Details anti-CD86 Antibody Application Details Handling References for anti-CD86 antibody (ABIN2661836) Images back to top
Antigen
Alternative Name CD86 (CD86 Antibody Abstract)
Background CD86 is an 80 kD member of the immunoglobulin superfamily also known as B70 or B7-2. It is expressed on antigen presenting cells and activated T and B cells. CD86 is a ligand for CD28 and CD152 (CTLA-4). It is one of the accessory molecules that plays an important role in T cell-APC cell costimulatory interactions. The 24F antibody can block the co-stimulatory activity of CD86.
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation

Application Details

Product Details anti-CD86 Antibody Target Details CD86 Handling References for anti-CD86 antibody (ABIN2661836) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD86 Antibody Target Details CD86 Application Details References for anti-CD86 antibody (ABIN2661836) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD86 antibody (ABIN2661836)

Product Details anti-CD86 Antibody Target Details CD86 Application Details Handling Images back to top
Background publications

Hu, Shen, Zhang, Zhang, Zhang, Zhang, Deng, Cao, Zhou, Chen, Ge, Xuan, Zhang, Jin: "Development of rat antigen-presenting cells from pluripotent ecto-mesenchymal stem cells in vitro and in vivo." in: Molecular immunology, Vol. 45, Issue 14, pp. 3818-26, 2008

Davidson, Wang, Mihara, Ramanujam, Huang, Schiffer, Sinha: "Co-stimulatory blockade in the treatment of murine systemic lupus erythematosus (SLE)." in: Annals of the New York Academy of Sciences, Vol. 987, pp. 188-98, 2003

Maeda, Sato, Azuma, Yagita, Okumura: "Characterization of rat CD80 and CD86 by molecular cloning and mAb." in: International immunology, Vol. 9, Issue 7, pp. 993-1000, 1997

Bluestone: "New perspectives of CD28-B7-mediated T cell costimulation." in: Immunity, Vol. 2, Issue 6, pp. 555-9, 1995

Freeman, Borriello, Hodes, Reiser, Hathcock, Laszlo, McKnight, Kim, Du, Lombard: "Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice." in: Science (New York, N.Y.), Vol. 262, Issue 5135, pp. 907-9, 1993

Hathcock, Laszlo, Dickler, Bradshaw, Linsley, Hodes: "Identification of an alternative CTLA-4 ligand costimulatory for T cell activation." in: Science (New York, N.Y.), Vol. 262, Issue 5135, pp. 905-7, 1993

Images

Product Details anti-CD86 Antibody Target Details CD86 Application Details Handling References for anti-CD86 antibody (ABIN2661836) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD86 Molecule (CD86) antibody (FITC) (ABIN2661836) anti-CD86 Molecule (CD86) antibody (FITC)