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|Antigen||Glutathione Reductase (GSR) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Glutathione Reductase antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-Glutathione Reductase AntibodyTarget Details Glutathione Reductase Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human GSR|
|Plasmids, Primers & others|
Target Details Glutathione ReductaseProduct Details anti-Glutathione Reductase Antibody Application Details Handling Images back to top
|Alternative Name||GLUR/glutathione Reductase (GSR Antibody Abstract)|
Glutathione reductase (GR) is a member of pyridine nucleotide- disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+?2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.
Synonyms: glutathione reductase, GLUR, Glutathione reductase mitochondrial, GR, Gr1, GRase, GRD 1, GRD1, GSR, MGC78522.
|Pathways||Thyroid Hormone Synthesis, Cell RedoxHomeostasis|
Application DetailsProduct Details anti-Glutathione Reductase Antibody Target Details Glutathione Reductase Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-Glutathione Reductase Antibody Target Details Glutathione Reductase Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
ImagesProduct Details anti-Glutathione Reductase Antibody Target Details Glutathione Reductase Application Details Handling back to top