anti-Mouse (Murine) IRF7 antibody for Immunoprecipitation

Recommended IRF7 Antibody (supplied by: Log in to see )

Antigen
Interferon Regulatory Factor 7 (IRF7) Antibodies
  • wu:fl24c03
  • zgc:66043
  • zgc:77947
  • IRF7
  • irf7
  • IRF-7H
  • IRF7A
  • IRF7B
  • IRF7C
  • IRF7H
  • interferon regulatory factor 7
  • irf7
  • IRF7
  • Irf7
Reactivity
Mouse (Murine), Rat (Rattus), Human
149
59
55
3
2
2
2
2
1
1
Host
Rabbit
107
42
Clonality
Polyclonal
Conjugate
This IRF7 antibody is un-conjugated
7
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
103
51
27
26
25
9
5
5
4
2
2
1
1
1
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Available images

Catalog No. ABIN3020651
$ 393.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN2736992 FACS IP WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Interferon Regulatory Factor 7 (IRF7) Antibodies
Reactivity Mouse (Murine), Rat (Rattus), Human
(149), (59), (55), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(107), (42)
Clonality
Polyclonal
Conjugate This IRF7 antibody is un-conjugated
(7), (6), (6), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
(103), (51), (27), (26), (25), (9), (5), (5), (4), (2), (2), (1), (1), (1)
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Product Details anti-IRF7 Antibody

Target Details IRF7 Application Details Handling Images
Purification Affinity purification
Immunogen A synthetic peptide of human IRF7
Isotype IgG
Plasmids, Primers & others

Target Details IRF7

Product Details anti-IRF7 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IRF7 (IRF7 Antibody Abstract)
Background Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3gamma/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ICSBP. All IRF proteins share homology in their amino-terminal DNA-binding domains. IRF family members regulate transcription through interactions with proteins that share similar DNA-binding motifs, such as IFN-stimulated response elements (ISRE), IFN consensus sequences (ICS), and IFN regulatory elements (IRF-E). IRF-7, which is functionally similar to IRF-3, is preferentially expressed in lymphoid cells and induced by virus, LPS, and IFN-alpha. IRF-7 plays an essential role in the induction of type I interferon in response viral infecton. Like IRF-3, IRF-7 is regulated at multiple serine phosphorylation sites near its carboxyl terminus, which are required for nuclear translocation, DNA binding, and transcriptional activity.
Synonyms: IRF7, IRF-7H, IRF7A, Interferon regulatory factor 7
Gene ID 3665
UniProt Q92985
Pathways TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy

Application Details

Product Details anti-IRF7 Antibody Target Details IRF7 Handling Images back to top
Application Notes Recommended dilutions: WB: 1:1000-1:2000, IP: 1:20-1:50, FC: 1:50-1:100
Restrictions For Research Use only

Handling

Product Details anti-IRF7 Antibody Target Details IRF7 Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-IRF7 Antibody Target Details IRF7 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Interferon Regulatory Factor 7 (IRF7) antibody (ABIN3020651) Western blot analysis of extracts of various cell lines, using IRF7 antibody.