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WISP2 Products

(WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

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This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq, Jul 2008].

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Featured WISP2 Categories

WISP2 Antibodies

High quality antibodies with extensive validation data.

WISP2 ELISA Kits

Reliable ELISA kits for a wide range of species.

WISP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WISP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN390188
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6150227
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (1)
  • (2)
Cat. No. ABIN948739
Quantity 100 μL
Datasheet Datasheet

Recommended WISP2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971204
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960561
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973573
Quantity 96 tests
Datasheet Datasheet

Recommended WISP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325343
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3075541
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7508309
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our WISP2 products

Ji, Jia, Jia, Ji, Hargest, Jiang: "WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." in: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).

Conde, Scotece, Abella, Gómez, López, Villar, Hermida, Pino, Gómez-Reino, Gualillo: "Identification of novel adipokines in the joint. Differential expression in healthy and osteoarthritis tissues." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123601, (2015) (PubMed).

Huang, Caputo, Noordmans, Yazdani, Monteiro, van den Born, van Goor, Heeringa, Korstanje, Hillebrands: "Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice." in: PloS one, Vol. 9, Issue 3, pp. e91850, (2015) (PubMed).

Banerjee, Saxena, Sengupta, Tawfik, Mayo, Banerjee: "WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferation." in: Neoplasia (New York, N.Y.), Vol. 5, Issue 1, pp. 63-73, (2003) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Synonyms and alternative names related to WISP2

WNT1 inducible signaling pathway protein 2 (WISP2), WNT1 inducible signaling pathway protein 2 S homeolog (wisp2.S), WNT1 inducible signaling pathway protein 2 (wisp2), WNT1 inducible signaling pathway protein 2 (Wisp2), ccn5, CCN5, Ccn5, Crgr4, CT58, CTGF-L, Ctgfl, MGC84196, Rcop1, WISP2

Protein level used designations for WISP2

  • WNT1 inducible signaling pathway protein 2
  • Wnt-1 inducible-signaling pathway protein 2
  • WNT1 inducible signaling pathway 2
  • zWISP2-c23
  • CCN family member 5
  • WISP-2
  • WNT1-inducible-signaling pathway protein 2
  • connective tissue growth factor-like protein
  • connective tissue growth factor-related protein 58
  • wnt-1 signaling pathway protein 2
  • CTGF-L
  • CCN family protein COP-1
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