WNT3 Products
(Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
Categories
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008].
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Featured WNT3 Categories
WNT3 Antibodies
High quality antibodies with extensive validation data.
WNT3 ELISA Kits
Reliable ELISA kits for a wide range of species.
WNT3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended WNT3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (8)
Cat. No.
ABIN1490901
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
- (4)
Cat. No.
ABIN185634
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1490900
Quantity
100 μL
Datasheet
Datasheet
Recommended WNT3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960541
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975653
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960542
Quantity
96 tests
Datasheet
Datasheet
Recommended WNT3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1325359
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3075575
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409761
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our WNT3 products
: "Altered miRNA-profile dependent on ART outcome in early pregnancy targets Wnt-pathway." in: Reproduction (Cambridge, England), Vol. 154, Issue 6, pp. 799-805, (2018) (PubMed).: "Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 31, pp. 10911-26, (2015) (PubMed).
: "Role of WNT10A-expressing kidney fibroblasts in acute interstitial nephritis." in: PLoS ONE, Vol. 9, Issue 7, pp. e103240, (2014) (PubMed).
: "Wnt protein-mediated satellite cell conversion in adult and aged mice following voluntary wheel running." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7399-412, (2014) (PubMed).
: "Wnt3 and Wnt3a are required for induction of the mid-diencephalic organizer in the caudal forebrain." in: Neural development, Vol. 7, pp. 12, (2012) (PubMed).
: "Expression of Wnt3 activates Wnt/?-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells." in: Molecular cancer research : MCR, Vol. 10, Issue 12, pp. 1597-606, (2012) (PubMed).
: "Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 10, pp. 3570-82, (2011) (PubMed).
: "Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping." in: Nature, Vol. 439, Issue 7072, pp. 31-7, (2006) (PubMed).
Synonyms and alternative names related to WNT3
Wnt family member 3 (WNT3), Wnt family member 3 (Wnt3), wingless-type MMTV integration site family, member 3 (wnt3), proto-oncogene Wnt-3 (LOC468297), wingless-type MMTV integration site family member 3 (WNT3), Wnt family member 3A (WNT3A), Wnt family member 3 (wnt3), wingless-type MMTV integration site family, member 3 (Wnt3), wingless-type MMTV integration site family member 3 L homeolog (wnt3.L), Ci-Wnt3, Int-4, INT4, int4, wnt-3, Wnt-3, WNT3, wnt3, wnt3-A, wnt3l, Xwnt-3, Xwnt3Protein level used designations for WNT3
- WNT-3 proto-oncogene protein
- proto-oncogene Int-4 homolog
- proto-oncogene Wnt-3
- Wingless-type MMTV integration site 3, homolog
- wingless-related MMTV integration site 3
- wingless-type MMTV integration site family member 3
- wingless-type MMTV integration site family, member 3
- wingless-related MMTV integration site 3A
- proto-oncogene Wnt-3-like
- proto-oncogene Int-4
- proto-oncogene protein Wnt-3
- Xwnt-3 region near C-terminus
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