anti-Mouse (Murine) CTNNB1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CTNNB1 Antibody (supplied by: Log in to see )

Antigen
Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
  • Jup
  • LOC100217813
  • CTNNB1
  • CTNNB
  • Bfc
  • Catnb
  • Mesc
  • ctnnb
  • id:ibd2058
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
  • ctnnb1
  • CHBCAT
  • MRD19
  • armadillo
  • beta-catenin
  • catenin beta 1
  • catenin (cadherin associated protein), beta 1
  • catenin (cadherin-associated protein), beta 1
  • catenin beta 1 S homeolog
  • catenin beta 1 L homeolog
  • CTNNB1
  • Ctnnb1
  • ctnnb1
  • ctnnb1.S
  • ctnnb1.L
Epitope
AA 764-781, C-Term
76
20
19
18
17
17
15
15
14
10
10
8
8
8
6
6
5
5
5
5
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
519
235
210
61
51
39
26
25
17
17
13
13
11
8
7
6
3
1
Host
Rabbit
336
197
8
2
Clonality
Polyclonal
Conjugate
This CTNNB1 antibody is un-conjugated
14
11
8
7
7
6
4
4
2
2
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
489
208
175
140
115
108
68
28
23
13
10
8
4
3
3
2
2
1
Options
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Catalog No. ABIN3044344
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
23.5 ABIN5518980 ELISA IHC (p) WB Rabbit IgG AA 2-233 Log in to see Polyclonal 1
20.5 ABIN5518651 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 1-19, N-Term Log in to see Polyclonal 15
19 ABIN1496898 IF IHC IHC (p) WB Mouse IgG2b Log in to see 9C1 0
17.5 ABIN5693091 IHC (p) WB Mouse IgG1 AA 2-233 Log in to see 1F6 12
12.579589 ABIN1689977 IHC (fro) IHC (p) WB Rabbit Log in to see Polyclonal 0
11.127748 ABIN337082 ELISA IHC IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal 0
11.127748 ABIN498724 IF IHC (p) Rabbit pSer33 Log in to see Polyclonal 0
11.127748 ABIN498725 IF IHC (p) WB Rabbit pSer37 Log in to see Polyclonal 0
11.127748 ABIN498604 IHC (p) WB Rabbit Log in to see Polyclonal 0
11.127748 ABIN498603 IF IHC (p) WB Rabbit Log in to see Polyclonal 0
10 ABIN197444 IF IHC (p) WB Rabbit Ser33 Log in to see Polyclonal 5
10 ABIN614788 FACS IF IHC (p) IP WB Mouse IgG1 Log in to see EM-22 3
10 ABIN196956 IF IHC (p) WB Rabbit pSer33 Log in to see Polyclonal 5
10 ABIN197446 IF IHC (p) WB Rabbit Ser37 Log in to see Polyclonal 5
10 ABIN574434 FACS ICC IHC IHC (p) IP WB Mouse IgG1 Log in to see EM-22 0
8.127748 ABIN2450412 IHC IHC (p) WB Rabbit IgG AA 43-62 Log in to see Polyclonal 0
8.127748 ABIN498825 IHC (p) Rabbit pSer45, pThr41 Log in to see Polyclonal 0
8.127748 ABIN498824 IHC (p) Rabbit pSer33, pSer37, pThr41 Log in to see Polyclonal 0
8.127748 ABIN498914 IHC (p) Rabbit Log in to see Polyclonal 0
7 ABIN196958 IHC (p) WB Rabbit pSer37 Log in to see Polyclonal 5

General

Antigen Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
Epitope AA 764-781, C-Term
(76), (20), (19), (18), (17), (17), (15), (15), (14), (10), (10), (8), (8), (8), (6), (6), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(519), (235), (210), (61), (51), (39), (26), (25), (17), (17), (13), (13), (11), (8), (7), (6), (3), (1)
Host Rabbit
(336), (197), (8), (2)
Clonality
Polyclonal
Conjugate This CTNNB1 antibody is un-conjugated
(14), (11), (8), (7), (7), (6), (4), (4), (2), (2), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(489), (208), (175), (140), (115), (108), (68), (28), (23), (13), (10), (8), (4), (3), (3), (2), (2), (1)
Pubmed 15 references available
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Product Details anti-CTNNB1 Antibody

Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN3044344) Images
Purpose Rabbit IgG polyclonal antibody for Catenin beta-1(CTNNB1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Sequence DGLPPGDSNQ LAWFDTDL
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Catenin beta-1(CTNNB1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: catenin(cadherin-associated protein), beta 1, 88 kDa
Protein Name: Catenin beta-1
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human beta Catenin(764-781aa DGLPPGDSNQLAWFDTDL), identical to the related rat and mouse sequences.
Isotype IgG
Plasmids, Primers & others

Target Details CTNNB1

Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 antibody (ABIN3044344) Images back to top
Antigen
Alternative Name CTNNB1 (CTNNB1 Antibody Abstract)
Background Catenins are proteins found in complexes with cadherin cell adhesion molecules of animal cells. The first two catenins that were identified became known as alpha-catenin and beta-catenin. Alpha-catenin can bind to beta-catenin and can also bind actin. Beta-catenin binds the cytoplasmic domain of some cadherins. Beta-catenin is an adherens junction protein. It plays an important role in various aspects of liver biology including liver development(both embryonic and postnatal), liver regeneration following partial hepatectomy. HGF-induced hepatpomegaly, liver zonation, and pathogenesis of liver cancer.

Synonyms: b-catenin antibody|Beta catenin antibody|Beta-catenin antibody|Cadherin associated protein antibody|Catenin(cadherin associated protein), beta 1, 88 kDa antibody|Catenin beta 1 antibody|Catenin beta-1 antibody|CATNB antibody|CHBCAT antibody| CTNB1_HUMAN antibody|CTNNB antibody|CTNNB1 antibody|DKFZp686D02253 antibod|FLJ25606 antibody|FLJ37923 antibody|OTTHUMP00000162082 antibody|OTTHUMP00000165222 antibody|OTTHUMP00000165223 antibody|OTTHUMP00000209288 antibody| OTTHUMP00000209289 antibody
UniProt P35222
Pathways WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 antibody (ABIN3044344) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions For Research Use only

Handling

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 antibody (ABIN3044344) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

References for anti-CTNNB1 antibody (ABIN3044344)

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top
Product cited in:

Ma, Lv, Sun, Ma, Xing, Wang, Sun, Wang, Li, Li, Zhao: "Naringin ameliorates bone loss induced by sciatic neurectomy and increases Semaphorin 3A expression in denervated bone." in: Scientific reports, Vol. 6, pp. 24562, 2018

Jia, Ma, Lv, Ma, Xu, Yang, Tian, Wang, Sun, Xu, Fu, Zhao: "Oestrogen and parathyroid hormone alleviate lumbar intervertebral disc degeneration in ovariectomized rats and enhance Wnt/β-catenin pathway activity." in: Scientific reports, Vol. 6, pp. 27521, 2018

Cong, Fu, Zhang, Zhao, Zhang: "Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 210-216, 2018

Guo, Yi, Li, Fu, Li: "Snail1 is positively correlated with atrial fibrosis in patients with atrial fibrillation and rheumatic heart disease." in: Experimental and therapeutic medicine, Vol. 14, Issue 5, pp. 4231-4237, 2017

Pan, An, Meng, Li, Ren, Guan: "MgCl2 and ZnCl2 promote human umbilical vein endothelial cell migration and invasion and stimulate epithelial-mesenchymal transition via the Wnt/β-catenin pathway." in: Experimental and therapeutic medicine, Vol. 14, Issue 5, pp. 4663-4670, 2017

Fu, Jiao, Zheng, Liang, Hu: "Combination of lithium chloride and pEGFP-N1-BmK CT effectively decreases proliferation and migration of C6 glioma cells." in: Cytotechnology, Vol. 68, Issue 2, pp. 197-202, 2016

Lei, Lai, Bai, Qiu, Yang, Liao, Chuong, Yang, Lian, Zhong: "Prolonged overexpression of Wnt10b induces epidermal keratinocyte transformation through activating EGF pathway." in: Histochemistry and cell biology, Vol. 144, Issue 3, pp. 209-21, 2016

Chen, Xue, Shen, Mu, Fu: "Curcumin alleviates glucocorticoid-induced osteoporosis through the regulation of the Wnt signaling pathway." in: International journal of molecular medicine, Vol. 37, Issue 2, pp. 329-38, 2016

Shan, Lv, Zhao, Liu, Sun, Xi, Xiao, Li: "Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells." in: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 12357-67, 2016

Lin, Sun, Wang, Zheng, Zhang, Zheng: "Celastrol Ameliorates Ulcerative Colitis-Related Colorectal Cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition." in: Frontiers in pharmacology, Vol. 6, pp. 320, 2016

Wang, Ge, Zhang, Chen, Hu, Li, Ye: "Targeted p53 activation by saRNA suppresses human bladder cancer cells growth and metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 35, pp. 53, 2016

Hao, Wen, Li, Wang, Ni, Wang, Wang, Sun, Fan, Mao: "LiCl inhibits PRRSV infection by enhancing Wnt/?-catenin pathway and suppressing inflammatory responses." in: Antiviral research, Vol. 117, pp. 99-109, 2015

Zhao, Li, Gao, Wang, Yan, Zhan, Liu, Mao, Chen, Wang et al.: "Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3? (GSK-3?) ..." in: European journal of medicinal chemistry, Vol. 86, pp. 165-74, 2014

Lyu, Wang, Wang, Ding, Liu, Yuan, Shi, Wang, Wang, Chen: "Maintaining the pluripotency of mouse embryonic stem cells on gold nanoparticle layers with nanoscale but not microscale surface roughness." in: Nanoscale, Vol. 6, Issue 12, pp. 6959-69, 2014

Lei, Guo, Qiu, Lai, Yang, Widelitz, Chuong, Lian, Yang: "Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration." in: Experimental dermatology, Vol. 23, Issue 6, pp. 407-13, 2014

Images

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN3044344) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 764-781), (C-Term) antibody (ABIN3044344) Anti-beta Catenin antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue
Western Blotting (WB) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 764-781), (C-Term) antibody (ABIN3044344) Anti-beta Catenin antibody, Western blotting Lane 1: MM453 Cell Lysate Lane 2: MCF-7 ...
Immunohistochemistry (IHC) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 764-781), (C-Term) antibody (ABIN3044344) Anti-beta Catenin antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue
Immunohistochemistry (IHC) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 764-781), (C-Term) antibody (ABIN3044344) Anti-beta Catenin antibody, IHC(F) IHC(F): Rat Intestine Tissue
Western Blotting (WB) image for anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 764-781), (C-Term) antibody (ABIN3044344) Lane 8: Cell Lysate