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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN575103 | WB | Rabbit | AA 143-192 | Log in to see | Polyclonal | 0 |
General |
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Antigen | Wingless-Type MMTV Integration Site Family, Member 3 (WNT3) Antibodies |
Epitope | Middle Region Alternatives |
Reactivity | Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This WNT3 antibody is un-conjugated Alternatives |
Application |
Western Blotting (WB)
Alternatives
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Supplier | Log in to see |
Product Details anti-WNT3 AntibodyTarget Details WNT3 Application Details Handling Images |
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Blocking Peptide | Blocking peptide for this product available: ABIN986218 |
Sequence | SHHKGPPGEG WKWGGCSEDA DFGVLVSREF ADARENRPDA RSAMNKHNNE |
Predicted Reactivity | Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93% |
Characteristics | This is a rabbit polyclonal antibody against WNT3. It was validated on Western Blot. |
Purification | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human WNT3 |
Target Details WNT3Product Details anti-WNT3 Antibody Application Details Handling Images back to top |
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Antigen | |
Alternative Name | WNT3 (WNT3 Antibody Abstract) |
Background |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. Alias Symbols: INT4, MGC131950, MGC138321, MGC138323 Protein Interaction Partner: FZD1, Protein Size: 355 |
Molecular Weight | 37 kDa |
Gene ID | 7473 |
NCBI Accession | NM_030753, NP_110380 |
UniProt | P56703 |
Pathways | WNT Signaling, Regulation of Cell Size |
Application DetailsProduct Details anti-WNT3 Antibody Target Details WNT3 Handling Images back to top |
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Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Comment |
Antigen size: 355 AA |
Restrictions | For Research Use only |
HandlingProduct Details anti-WNT3 Antibody Target Details WNT3 Application Details Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
ImagesProduct Details anti-WNT3 Antibody Target Details WNT3 Application Details Handling back to top |
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Supplier Images |