CUB Domain Containing Protein 1 Proteins (CDCP1)

The protein encoded by CDCP1 is a transmembrane protein containing three extracellular CUB domains. Additionally we are shipping CUB Domain Containing Protein 1 Antibodies (183) and CUB Domain Containing Protein 1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CDCP1 64866 Q9H5V8
CDCP1 109332 Q5U462
Rat CDCP1 CDCP1 301082  
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Top CUB Domain Containing Protein 1 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Human Cells Human Fc Tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Human Cells Rhesus Monkey His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Human Human His tag   10 μg Log in to see 15 to 16 Days
$225.00
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$404.25
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
$641.43
Details

CDCP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , , , ,
Mouse (Murine) ,
, ,

Top referenced CUB Domain Containing Protein 1 Proteins

  1. Rhesus Monkey CDCP1 Protein expressed in Human Cells - ABIN2010111 : Conze, Lammers, Kuci, Scherl-Mostageer, Schweifer, Kanz, Buhring: CDCP1 is a novel marker for hematopoietic stem cells. in Annals of the New York Academy of Sciences 2003 (PubMed)
    Show all 2 references for 2010111

  2. Human CDCP1 Protein expressed in Human Cells - ABIN2005620 : Scherl-Mostageer, Sommergruber, Abseher, Hauptmann, Ambros, Schweifer: Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. in Oncogene 2001 (PubMed)
    Show all 2 references for 2005620

  3. Human CDCP1 Protein expressed in HEK-293 Cells - ABIN2713643 : Sandercock, Rust, Guillard, Sachsenmeier, Holoweckyj, Hay, Flynn, Huang, Yan, Herpers, Price, Soden, Freeth, Jermutus, Hollingsworth, Minter: Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling. in Molecular cancer 2015 (PubMed)

More Proteins for CUB Domain Containing Protein 1 (CDCP1) Interaction Partners

Human CUB Domain Containing Protein 1 (CDCP1) interaction partners

  1. These studies have important implications for the development of a therapeutic to block CDCP1 activity and Triple-negative breast cancer (TNBC)metastasis.

  2. CDCP1 may facilitate loss of adhesion by promoting activation of EGFR (show EGFR Proteins) and Src (show SRC Proteins) at sites of cell-cell and cell-substratum contact.

  3. Stromal expression patterns for both ADAM12 (show ADAM12 Proteins) and CDCP1.

  4. these data demonstrated that HIF-2alpha (show EPAS1 Proteins) could promote hepatocellular carcinoma cell migration by regulating CDCP1

  5. Our results establish that differential glycosylation, cell surface presentation and extracellular expression of CDCP1 are hallmarks of prostate cancer progression.

  6. High CDCP1 expression is associated with Colorectal Cancer.

  7. ADAM9 (show ADAM9 Proteins) enhances CDCP1 protein expression by suppressing miR (show MLXIP Proteins)-218 for lung tumor metastasis

  8. Elevated CDCP1 was observed in 77% of HGSC cases. Silencing of CDCP1 reduced migration and non-adherent cell growth in vitro and tumour burden in vivo.

  9. CDCP1 protein plays an important role in the progression of ovarian clear cell carcinoma. Elevated CDCP1 levels correlates with poor patient outcome in ovarian clear cell carcinoma patients.

  10. CDCP1 overexpression enhances HER2 (show ERBB2 Proteins) activity. CDCP1 binds to HER2 (show ERBB2 Proteins), promoting SRC (show SRC Proteins)-HER2 (show ERBB2 Proteins) crosstalk.

Mouse (Murine) CUB Domain Containing Protein 1 (CDCP1) interaction partners

  1. Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor (show RYK Proteins) cross-talk in unanchored cells.

  2. established mechanism for initiation of CDCP1-mediated signaling; demonstrated that processing of surface CDCP1 by extracellular serine proteases is prerequisite for CDCP1-dependent survival of cancer cells during metastasis; preventing cleavage of CDCP1 abrogated survival signaling associated with CDCP1 and induced PARP1 (show PARP1 Proteins) cleavage and PARP1 (show PARP1 Proteins)-mediated apoptosis

  3. CDCP1 may have a role in neoplasm metastasis; targeting it with a monoclonal antibody inhibits metastasis in a prostate cancer model

CUB Domain Containing Protein 1 (CDCP1) Protein Profile

Protein Summary

The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene names and symbols associated with CDCP1

  • CUB domain containing protein 1 (CDCP1)
  • CUB domain containing protein 1 (Cdcp1)
  • 9030022E12Rik protein
  • AA409659 protein
  • CD318 protein
  • E030027H19Rik protein
  • RGD1305578 protein
  • SIMA135 protein
  • TRASK protein

Protein level used designations for CDCP1

CUB domain-containing protein 1 , membrane glycoprotein gp140 , subtractive immunization M plus HEp3-associated 135 kDa protein , transmembrane and associated with src kinases

GENE ID SPECIES
64866 Homo sapiens
109332 Mus musculus
301082 Rattus norvegicus
420703 Gallus gallus
484797 Canis lupus familiaris
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