CDCP1 Protein (AA 30-368) (His tag)
-
- Target See all CDCP1 Proteins
- CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-368
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CDCP1 protein is labelled with His tag.
- Purpose
- Human CDCP1 (30-368) Protein
- Sequence
- Phe30-Arg368
- Characteristics
- Recombinant Human CDCP1 (30-368) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe30-Arg368.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CDCP1 (30-368) , His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 13.2ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CDCP1 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in 20 mM PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
- Alternative Name
- CDCP1 (CDCP1 Products)
- Synonyms
- CD318 Protein, SIMA135 Protein, TRASK Protein, 9030022E12Rik Protein, AA409659 Protein, E030027H19Rik Protein, RGD1305578 Protein, zgc:113071 Protein, CUB domain containing protein 1 Protein, CUB domain containing protein 1a Protein, CDCP1 Protein, Cdcp1 Protein, cdcp1a Protein
- Background
- Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
- Molecular Weight
- 39.03 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
-