CDCP1 Protein (His tag)
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- Target See all CDCP1 Proteins
- CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
- Protein Type
- Recombinant
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CDCP1 protein is labelled with His tag.
- Sequence
- Ala29-Thr667
- Purity
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus CDCP1 at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CDCP1 Ab., hFc Tag with the EC50 of 23.7ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CDCP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
- Alternative Name
- CDCP1 (CDCP1 Products)
- Synonyms
- CD318 Protein, SIMA135 Protein, TRASK Protein, 9030022E12Rik Protein, AA409659 Protein, E030027H19Rik Protein, RGD1305578 Protein, zgc:113071 Protein, CUB domain containing protein 1 Protein, CUB domain containing protein 1a Protein, CDCP1 Protein, Cdcp1 Protein, cdcp1a Protein
- Background
- CDCP1, CD318, SIMA135, TRASK, UNQ2486, PRO5773,Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
- Molecular Weight
- 73.2 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- XP_001114659
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