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CDCP1 Protein (Fc Tag)

CDCP1 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Catalog No. ABIN7274294
  • Target See all CDCP1 Proteins
    CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
    Protein Type
    Recombinant
    Origin
    • 15
    • 7
    • 2
    • 1
    Human
    Source
    • 15
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CDCP1 protein is labelled with Fc Tag.
    Sequence
    Phe30-Leu666
    Purity
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human CDCP1, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CDCP1 Antibody, hFc Tag with the EC50 of 15.3ng/ml determined by ELISA. See testing image for detail.
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    Discover our top product CDCP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Storage
    4 °C,-80 °C
    Storage Comment
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
    Alternative Name
    CDCP1 (CDCP1 Products)
    Synonyms
    CD318 Protein, SIMA135 Protein, TRASK Protein, 9030022E12Rik Protein, AA409659 Protein, E030027H19Rik Protein, RGD1305578 Protein, zgc:113071 Protein, CUB domain containing protein 1 Protein, CUB domain containing protein 1a Protein, CDCP1 Protein, Cdcp1 Protein, cdcp1a Protein
    Background
    CDCP1, CD318, SIMA135, TRASK, UNQ2486, PRO5773,Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
    Molecular Weight
    98.4 kDa. Due to glycosylation, the protein migrates to 115-130 kDa based on Tris-Bis PAGE result.
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