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anti-Deiodinase, Iodothyronine, Type I (DIO1) Antibodies

The protein encoded by DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. Additionally we are shipping DIO1 Kits (12) and DIO1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DIO1 1733 P49895
DIO1 13370 Q61153
DIO1 25430 P24389
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Top anti-DIO1 Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of DIO1 Antibody (N-term) (ABIN390946) in HepG2 cell line lysates (35 µg/lane). DIO1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

DIO1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
,
,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-DIO1 Antibodies

  1. Human Polyclonal DIO1 Primary Antibody for WB - ABIN390946 : Landa, Ruiz-Llorente, Montero-Conde, Inglada-Pérez, Schiavi, Leskelä, Pita, Milne, Maravall, Ramos, Andía, Rodríguez-Poyo, Jara-Albarrán, Meoro, del Peso, Arribas, Iglesias, Caballero, Serrano, Picó, Pomares, Giménez, López-Mondéjar, Castello, Merante-Bos: The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors. in PLoS genetics 2009 (PubMed)

More Antibodies against DIO1 Interaction Partners

Human Deiodinase, Iodothyronine, Type I (DIO1) interaction partners

  1. All these results indicate that the oxidative stress downregulates the conversion of T4 to T3 through DIO1 (show DIDO1 Antibodies) function in HepG2 cells.

  2. Thyroid hormone (show PTH Antibodies) deiodinases D1, D2, and D3 are differentially expressed in endothelial cells following thyroid hormone (show PTH Antibodies) exposure.

  3. The pattern of expression and role of triiodothyronine (T3) receptors and type I 5'-deiodinase in breast carcinomas, benign breast diseases, lactational change, and normal breast epithelium.

  4. [review] Deiodinase type 1 polymorphisms particularly show moderate-to-strong relationships with thyroid hormone (show PTH Antibodies) parameters, insulin (show INS Antibodies)-like growth factor (IGF)1 (show IGF1 Antibodies) protein production, and risk for depression.

  5. a new mechanism of posttranscriptional regulation of DIO1 (show DIDO1 Antibodies) and show deregulation of DIO1 (show DIDO1 Antibodies) expression in pituitary adenoma, possibly resulting from disturbed expression of SF2/ASF (show SRSF1 Antibodies).

  6. Data indicate that type 1 deiodinase is subject to catalysis-induced loss of activity.

  7. investigation of DIO1 (show DIDO1 Antibodies) and DIO2 (show DIO2 Antibodies) activities in 66 thyroid tissue samples from follicular thyroid adenoma, toxic diffuse goiter, nontoxic multinodular goiter, papillary thyroid carcinoma, and surrounding normal tissues

  8. Short interfering RNA-mediated knockdown of FOXA1 (show FOXA1 Antibodies) decreased the expression of DIO1 (show DIDO1 Antibodies) mRNA, but knockdown of both FOXA1 (show FOXA1 Antibodies) and FOXA2 (show FOXA2 Antibodies) restored it.

  9. a novel miRNA-mediated regulatory mechanism of Type 1 iodothyronine deiodinase expression in clear cell Renal Cell Carcinoma (show MOK Antibodies)

  10. we report that SNP at the DIO1 (show DIDO1 Antibodies) variant rs11206244 is associated with lifetime major depression in White females in high-risk cohorts.

Mouse (Murine) Deiodinase, Iodothyronine, Type I (DIO1) interaction partners

  1. Systemic changes in thyroid hormone (show PTH Antibodies) economy as a result of acute food deprivation are not dependent on the deiodinases D1 or D2 but are mediated in part by sequestration of type4 and type3 in tissues and their enhanced metabolism by deiodinase D3.

  2. Results demonstrate changes in D1 activity in white adipose tissue under conditions of changing adiposity, and a stimulatory effect of leptin (show LEP Antibodies) on D1 activity in the tissue.

  3. A decreased hepatic D1 activity could be the biochemical basis of some of the abnormal thyroid parameters observed in cystic fibrosis (show S100A8 Antibodies)

  4. The type 1 deiodinase (D1) is an important source of Triiodothyronine in the euthyroid state.

  5. HNF4alpha (show HNF4A Antibodies) regulates thyroid hormone (show PTH Antibodies) homeostasis through transcriptional regulation of the Dio1 gene with GATA4 (show GATA4 Antibodies) and KLF9 (show KLF9 Antibodies)

Pig (Porcine) Deiodinase, Iodothyronine, Type I (DIO1) interaction partners

DIO1 Antigen Profile

Protein Summary

The protein encoded by this gene is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD). Alternative splicing results in multiple transcript variants encoding different isoforms. Some, but not all, isoforms contain a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Additional transcript variants have been described but are not supported by experimental evidence.

Gene names and symbols associated with DIO1

  • deiodinase, iodothyronine, type I (LOC100231867) antibody
  • deiodinase, iodothyronine, type 1 (dio1) antibody
  • deiodinase, iodothyronine, type I (DIO1) antibody
  • deiodinase, iodothyronine, type I (Dio1) antibody
  • 5DI antibody
  • D1 antibody
  • DIOI antibody
  • ITDI1 antibody
  • TXDI1 antibody

Protein level used designations for DIO1

5DI , DIOI , deiodinase, iodothyronine, type I , type 1 DI , type 1 deiodinase , type I iodothyronine deiodinase , type-I 5'-deiodinase , thyroxine deiodinase type I (selenoprotein) , thyroxine deiodinase, type I , thyroxine deiodinase type 1 , Type 1 DI , Type-I 5'-deiodinase

GENE ID SPECIES
100231867 Taeniopygia guttata
733447 Xenopus laevis
1733 Homo sapiens
13370 Mus musculus
25430 Rattus norvegicus
403635 Canis lupus familiaris
395940 Gallus gallus
414380 Sus scrofa
100101570 Oryctolagus cuniculus
493798 Felis catus
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