Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. Additionally we are shipping Interleukin 31 Antibodies (116) and Interleukin 31 Kits (45) and many more products for this protein.
Showing 10 out of 41 products:
In a CML (show BCR Proteins) patient with pruritus receiving imatinib mesylate, IL-31 and IL-33 (show IL33 Proteins) serum levels were significantly higher than controls. Imatinib could cause keratinocyte injury, the release of IL-33 (show IL33 Proteins), and the consequent interaction with its receptor on mast cells, inducing IL-31 secretion. The IL-31/IL-33 (show IL33 Proteins) axis may be involved in the pathogenesis of skin side effects related to imatinib mesylate treatment.
Distinct polymorphic variants of the IL-31 gene may be involved in the patho-genesis of mastocytosis, and IL-31 may be involved in the induction of pruritus in patients with mastocytosis.
Serum/pleural fluid IL-31 levels are elevated in tuberculous pleural effusion.
both SCF (show KITLG Proteins) and IL-31 play an important role in mediating inflammation and enhancing severity of atopic asthma.
IL-31 affects keratinocyte differentiation in multiple ways and the IL-1 (show IL1A Proteins) cytokine network is a major downstream effector of IL-31 signaling in deregulating the physical skin barrier.
Oncostatin M (show OSM Proteins) and interleukin-31: Cytokines, receptors, signal transduction and physiology.
The results of our analyses regarding serum levels and receptor expression do not suggest a central role of IL-31 in Mycosis fungoides/Sezary syndrome pathogenesis.
In summary, TGF-beta1 (show TGFB1 Proteins) and IL-31 were linked to progression from chronic hepatitis B to liver cirrhosis, and correlated well with the severity of disease.
An increase of IL-31 serum levels in postmenopausal women with decreased bone mineral density, is shown.
a possible systemic involvement of IL-31 and the absence of a systemic involvement of IL-33 (show IL33 Proteins) in allergic contact dermatitis.
IL-31 upregulates IL-31RA (show IL31RA Proteins) expression in DRG neuron cell bodies, and cutaneous-injected IL-31-induced itching is enhanced by DRG IL-31RA (show IL31RA Proteins) expression in mice
our results suggest a functional cooperation between NFAT1 (show NFAT1 Proteins) and JunB (show JUNB Proteins) in mediating IL-31 gene expression in CD4 (show CD4 Proteins)(+) T cells
Data not only illustrate various functions that cysteines perform during IL-31 biosynthesis and secretion, but also highlight their potential roles in cytokine effector functions.
IL-31 may be involved in promoting the dermatitis and epithelial responses that characterize allergic and non-allergic diseases
IL-31 interaction with IL-31 receptor (IL-31R) is identified in an acute model of T helper cell type 2 inflammation in the lung.
these data provide the first evidence of a function for IL-31-IL-31R interactions in limiting the magnitude of type 2 inflammatory responses within the intestine.
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004