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MHC Class I Polypeptide-Related Sequence A Proteins (MICA)

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. Additionally we are shipping MICA Antibodies (178) and MICA Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse MICA MICA 71775 Q9DBD0
MICA 4276  
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Top MICA Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 9 to 11 Days
$330.00
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 12 Days
$157.30
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 5 to 7 Days
$187.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MICA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , ,

Top referenced MICA Proteins

  1. Human MICA Protein expressed in HEK-293 Cells - ABIN2181502 : Groh, Steinle, Bauer, Spies: Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 3 references for ABIN2181502

  2. Human MICA Protein expressed in Human Cells - ABIN2005167 : Xiang, Liu, Zheng, Liu, Lv, Gao, Hu, Lam, Chan, Yang, Chen, Tsao, Bonneville, Lau, Tu: Targeted activation of human V?9V?2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease. in Cancer cell 2014 (PubMed)
    Show all 2 references for ABIN2005167

More Proteins for MHC Class I Polypeptide-Related Sequence A (MICA) Interaction Partners

Mouse (Murine) MHC Class I Polypeptide-Related Sequence A (MICA) interaction partners

  1. Murine inhibitor of carbonic anhydrase was a glycoprotein that associated with carbonic anhydrase in a 1:1 stoichiometry.[ICA]

Human MHC Class I Polypeptide-Related Sequence A (MICA) interaction partners

  1. Our results suggest that locally sustained expression of MICA and MICB (show MICB Proteins) in the tumor may contribute to the malignant progression of Gastric cancer(GC) and that expression of these ligands predicts an unfavorable prognosis in GC patients presenting large tumors.

  2. In South Tunisian population, MICA plays a disease modifying role, rather than being an important gene in the susceptibility for developing of uveitis.

  3. The reduced cell surface expression of NKG2D (show KLRK1 Proteins) in response to engagement by MICA-129Met variants appeared to reduce the severity of acute graft-versus-host disease.

  4. Estrogen upregulates MICA/B expression in human non-small cell lung cancer through the regulation of ADAM17 (show ADAM17 Proteins).

  5. This meta-analysis shows that the MICA-TM A6 allele and the MICA*009 allele are associated with BD susceptibility in various ethnic populations, and that MICA alleles are in strong linkage disequilibrium with HLA-B51 in BD.

  6. The importance of the functional MICA-129 polymorphism in the severity of left ventricular ejection fraction in Chronic Chagas heart disease was addressed.

  7. MICA polymorphisms do not appear to influence the development of ocular lesions in patients diagnosed with toxoplasmosis in this study population.

  8. The study investigates the link between Behcet's Disease and two specific HLA alleles associated with Behcet's Disease (HLA-A*26:01 and HLA-B*51:01) in terms of their binding affinity to the MICA.

  9. In conclusion DNT (show NT5C Proteins) cell can significantly inhibit the growth of pancreatic carcinoma in vivo, and the mechanism may be involved in abnormal expressions of MICA and NKG2D (show KLRK1 Proteins).

  10. Further studies of the association between HBV replication and MICA induction should be conducted.

MICA Protein Profile

Protein Summary

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MICA

  • RIKEN cDNA 1300017J02 gene (1300017J02Rik)
  • MHC class I polypeptide-related sequence A (MICA)
  • FLJ60820 protein
  • Ica protein
  • MGC111087 protein
  • MIC-A protein
  • mICA protein
  • PERB11.1 protein

Protein level used designations for MICA

inhibitor of carbonic anhydrase , MHC class I polypeptide-related sequence A , HLA class I antigen , Stress inducible class I homolog , MHC class I chain-related protein A , MHC class I chain-related gene A protein , stress inducible class I homolog , F10 alpha chain-like , class I histocompatibility antigen

GENE ID SPECIES
71775 Mus musculus
4276 Homo sapiens
100507436 Homo sapiens
417067 Gallus gallus
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