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MHC Class I Polypeptide-Related Sequence A Proteins (MICA)

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. Additionally we are shipping MICA Antibodies (141) and MICA Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse MICA MICA 71775 Q9DBD0
MICA 4276  
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Top MICA Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human MICA, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
$280.50
Details
HOST_Human Human His tag   10 μg Log in to see 11 Days
$212.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 9 to 11 Days
$330.00
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 12 Days
$157.30
Details

MICA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, , ,

Top referenced MICA Proteins

  1. Human MICA Protein expressed in HEK-293 Cells - ABIN2181502 : Groh, Steinle, Bauer, Spies: Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 3 references for ABIN2181502

  2. Human MICA Protein expressed in Human Cells - ABIN2005167 : Xiang, Liu, Zheng, Liu, Lv, Gao, Hu, Lam, Chan, Yang, Chen, Tsao, Bonneville, Lau, Tu: Targeted activation of human V?9V?2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease. in Cancer cell 2014 (PubMed)
    Show all 2 references for ABIN2005167

More Proteins for MHC Class I Polypeptide-Related Sequence A (MICA) Interaction Partners

Mouse (Murine) MHC Class I Polypeptide-Related Sequence A (MICA) interaction partners

  1. Murine inhibitor of carbonic anhydrase was a glycoprotein that associated with carbonic anhydrase in a 1:1 stoichiometry.[ICA]

Human MHC Class I Polypeptide-Related Sequence A (MICA) interaction partners

  1. MICA*012:05 differs from MICA*012:01 by a single synonymous C to T substitution at nucleotide position 269 in exon

  2. there is no obvious correlation between the MMP9 (show MMP9 Proteins) -1562 C/T SNP and the concentrations of circulating MICA/B in the breast cancer patients.

  3. Cirrhotic patients who carry MICA risk alleles and those without risk alleles but with high sMICA levels possessed the highest risk of HCC (show FAM126A Proteins) development once they failed antiviral therapy.

  4. High levels of serum MICA is associated with acute myocardial infarction.

  5. Findings shown here are important from an anthropologic perspective and will inform future studies of the potential role of MICA and MICB (show MICB Proteins) genes in allogeneic organ transplantation and HLA-linked disease association in populations of related ancestry.

  6. MICA was significantly associated with the epithelial-to-mesenchymal transition gene set in clear cell renal cell carcinoma (show MOK Proteins)

  7. Reversal of epigenetic silencing of MICA and MICB (show MICB Proteins) improves immune recognition and killing of Merkel cell carcinoma cells.

  8. Our meta-analysis confirmed MICA-A6 could be responsible for BD in three ethnic regions and should probably be treated as a risk factor for Behcet's disease.

  9. IFN-gamma (show IFNG Proteins) rs2069727 and MICA rs2596542 polymorphisms may be related to the incidence of hepatocellular carcinoma.

  10. gastric cancer patients who have tumors with high expression of MICA are more likely to benefit from adjuvant chemotherapy, immunotherapy and gastrectomy

MICA Protein Profile

Protein Summary

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MICA

  • RIKEN cDNA 1300017J02 gene (1300017J02Rik)
  • MHC class I polypeptide-related sequence A (MICA)
  • FLJ60820 protein
  • Ica protein
  • MGC111087 protein
  • MIC-A protein
  • mICA protein
  • PERB11.1 protein

Protein level used designations for MICA

inhibitor of carbonic anhydrase , MHC class I polypeptide-related sequence A , HLA class I antigen , Stress inducible class I homolog , MHC class I chain-related protein A , MHC class I chain-related gene A protein , stress inducible class I homolog , F10 alpha chain-like , class I histocompatibility antigen

GENE ID SPECIES
71775 Mus musculus
4276 Homo sapiens
100507436 Homo sapiens
417067 Gallus gallus
Selected quality suppliers for MICA Proteins (MICA)
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