You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) Antibodies

The protein encoded by NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. Additionally we are shipping Neutrophil Cytosolic Factor 4, 40kDa Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NCF4 17972 P97369
NCF4 500904  
NCF4 4689 Q15080
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Neutrophil Cytosolic Factor 4, 40kDa Antibodies at antibodies-online.com

Showing 10 out of 111 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NCF4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN190755 (0.5µg/ml) staining of Daudi cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of NCF4 antibody (C-term) (ABIN391905) in K562 cell line lysates (35 µg/lane). NCF4 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lymphoma reacted with NCF4 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged NCF4 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-NCF4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Muscle WB Suggested Anti-NCF4  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human ovary, using p40 phox (Phospho-Thr154) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human ovary tissue, using p40 phox (Ab-154) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

NCF4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , , ,


, , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , ,
Human , , , ,
, ,
,
, , , , , , , , , , , , , ,

Top referenced anti-Neutrophil Cytosolic Factor 4, 40kDa Antibodies

  1. Human Monoclonal NCF4 Primary Antibody for ELISA - ABIN393677 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393677

  2. Human Polyclonal NCF4 Primary Antibody for FACS, IHC (p) - ABIN391905 : Glas, Seiderer, Pasciuto, Tillack, Diegelmann, Pfennig, Konrad, Schmechel, Wetzke, Török, Stallhofer, Jürgens, Griga, Klein, Epplen, Schiemann, Mussack, Lohse, Göke, Ochsenkühn, Folwaczny, Müller-Myhsok, Brand: rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. in The American journal of gastroenterology 2009 (PubMed)
    Show all 2 references for ABIN391905

  3. Cow (Bovine) Polyclonal NCF4 Primary Antibody for WB - ABIN2782429 : Chen, He, Minshall, Dinauer, Ye: Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production. in The Journal of biological chemistry 2007 (PubMed)

  4. Dog (Canine) Polyclonal NCF4 Primary Antibody for EIA, IHC (p) - ABIN374770 : Rioux, Xavier, Taylor, Silverberg, Goyette, Huett, Green, Kuballa, Barmada, Datta, Shugart, Griffiths, Targan, Ippoliti, Bernard, Mei, Nicolae, Regueiro, Schumm, Steinhart, Rotter, Duerr, Cho, Daly et al.: Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. ... in Nature genetics 2007 (PubMed)

More Antibodies against Neutrophil Cytosolic Factor 4, 40kDa Interaction Partners

Mouse (Murine) Neutrophil Cytosolic Factor 4, 40kDa (NCF4) interaction partners

  1. p40phox deficiency leads to upregulation of chemokine receptor 1 (show CMKLR1 Antibodies) and downregulation of fucosyltransferases and sialyltransferases involved in glycan modifications during experimental intestinal inflammation.

  2. cooperation of p40(phox) with p47(phox) for Nox2 (show CYBB Antibodies)-based NADPH oxidase (show NOX1 Antibodies) activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis

  3. The defect in Reactive Oxygen Species production and killing of s aureus by p40(phox-/-) neutrophils defines p40(phox) as an essential component in bacterial killing.

  4. p40 (show LANCL1 Antibodies)(phoxR58A/R58A) embryos do not develop normally but p40 (show LANCL1 Antibodies)(phoxR58A/-) mice are viable and neutrophils from these animals exhibit significantly reduced oxidase responses compared to those from their p40(phox+/-) siblings.

  5. Class III PI3K Vps34 (show PIK3C3 Antibodies) is responsible for the synthesis of PtdIns(3)P on phagosomes containing either S aureus or E coli. PtdIns(3)P binding to p40(phox) is important for CD18 (show ITGB2 Antibodies)-dependent activation oxidase activation in response to S aureus and E coli

  6. p40(phox) is prephosphorylated in resting endothelial cells and can compensate p47(phox) in keeping basal ROS (show ROS1 Antibodies) production.

Human Neutrophil Cytosolic Factor 4, 40kDa (NCF4) interaction partners

  1. NCF4 polymorphism was associated with Crohn's disease, but not ulcerative colitis in Caucasian--{REVIEW}

  2. NCF4 may induce ex- pression of NADPH oxidase (show NOX1 Antibodies) enzymes, such as p67phox (show NCF2 Antibodies), p47phox (show NCF1 Antibodies), p22phox (show CYBA Antibodies) and NOX2 (show CYBB Antibodies), which lead to increased ROS (show ROS1 Antibodies) levels.

  3. Germline variation in NCF4, an innate immunity gene, is associated with an increased risk of colorectal cancer.

  4. The contribution of the functionally relevant NADPH (show NQO1 Antibodies) polymorphisms rs1883112 and rs4673 to anthracycline-related heart lesions provides a plausible explanation for their modulation of cardiotoxicity.

  5. Constitutive and inducible intracellular production of reactive oxygen species (ROS (show ROS1 Antibodies)) is higher in B cells expressing functional p40phox, supporting a direct role for p40phox in regulating B cell intracellular ROS (show ROS1 Antibodies) generation.

  6. Genome-wide association studies-reported associations between the NELL1, NCF4, and FAM92B genes and susceptibility to Crohn's disease could not be replicated in Canadian children and young adults.

  7. Younger age at diagnosis, complicated disease behavior, and ileal disease location are risk factors for perianal CD. First report of an association of the NCF4 gene with perianal disease.

  8. cooperation of p40(phox) with p47(phox) for Nox2 (show CYBB Antibodies)-based NADPH oxidase (show NOX1 Antibodies) activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis

  9. Results demonstrate that PBEF (show NAMPT Antibodies) can prime for PMN (show TBCE Antibodies) respiratory burst activity by promoting p40 (show IL9 Antibodies) and p47 (show ING1 Antibodies) translocation to the membrane.

  10. cytosolic localisation depends on direct interaction with F-actin

Cow (Bovine) Neutrophil Cytosolic Factor 4, 40kDa (NCF4) interaction partners

  1. Study proposes that NCF4 splice variants generated by functional SNP are important risk factors for mastitis susceptibility in dairy cows.

Neutrophil Cytosolic Factor 4, 40kDa (NCF4) Antigen Profile

Protein Summary

The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with NCF4

  • p40phox protein (p40phox) antibody
  • neutrophil cytosolic factor 4 (LOC100136241) antibody
  • neutrophil cytosolic factor 4 (Ncf4) antibody
  • neutrophil cytosolic factor 4, 40kDa (NCF4) antibody
  • AI451400 antibody
  • NCF antibody
  • P40PHOX antibody
  • SH3PXD4 antibody

Protein level used designations for NCF4

p40phox protein , neutrophil cytosolic factor 4 , NADPH oxidase cytosolic protein p40phox , NCF-4 , neutrophil NADPH oxidase factor 4 , neutrophil cytosol factor 4 , p40-phox , SH3 and PX domain-containing protein 4

GENE ID SPECIES
445891 Takifugu rubripes
100136241 Oncorhynchus mykiss
17972 Mus musculus
500904 Rattus norvegicus
4689 Homo sapiens
481277 Canis lupus familiaris
507859 Bos taurus
100009359 Oryctolagus cuniculus
Selected quality suppliers for anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) Antibodies
Did you look for something else?