You are viewing an incomplete version of our website. Please click to reload the website as full version.

PR Domain Containing 2, with ZNF Domain Proteins (PRDM2)

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. Additionally we are shipping PRDM2 Antibodies (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRDM2 7799 Q13029
Mouse PRDM2 PRDM2 110593  
Rat PRDM2 PRDM2 313678 Q63755
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top PRDM2 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human GST tag 100 μg Log in to see 2 to 3 Days
$252.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human GST tag RIZ1 protein gel. RIZ1 run on an SDS-PAGE gel and stained with Coomassie blue. 200 μg Log in to see 1 to 2 Days
$455.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PRDM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

Top referenced PRDM2 Proteins

  1. Human PRDM2 Protein expressed in Escherichia coli (E. coli) - ABIN2004102 : Shapiro, Lee, Winoto: Identification and cloning of the G3B cDNA encoding a 3' segment of a protein binding to GATA-3. in Gene 1995 (PubMed)
    Show all 5 references for ABIN2004102

More Proteins for PR Domain Containing 2, with ZNF Domain (PRDM2) Interaction Partners

Human PR Domain Containing 2, with ZNF Domain (PRDM2) interaction partners

  1. RIZ1 expression is negatively correlated with glioma differentiation and can serve as a predictor of glioma prognosis and thus could be a potential therapeutic target for patients with gliomas.

  2. Loss of RIZ1 expression due to methylation is associated with Renal Cell Carcinoma (show MOK Proteins).

  3. PRDM2 downregulation may play a role in dopamine-agonist resistance and tumor recurrence in prolactinomas.

  4. Results suggest that high expression of SMYD3 (show SMYD3 Proteins) is related to the occurrence of esophageal squamous cell carcinoma. Also, its suppression promoted the expression of RIZ1 suggesting a signal transduction pathway between SMYD3 (show SMYD3 Proteins) and RIZ1.

  5. PRDM2, PRDM5 (show PRDM5 Proteins), PRDM16 (show PRDM16 Proteins) promoters are methylated and their expression is suppressed in lung cancer cells.

  6. The development and progression of esophageal squamous cell carcinoma are related to the inactivation of RIZ1.

  7. RIZ1 expression is significantly downregulated as the formation of meningiomas progressed, and suggest that RIZ1 may represent a promising candidate tumor suppressor gene that contributes to malignant meningiomas.

  8. Reduction of RIZ1 expression aggravates the progression of liver fluke-related cholangiocarcinoma

  9. Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype

  10. Data suggest that promoter methylation may play an important role in the epigenetic silencing of RIZ1 gene expression in human esophageal squamous cell carcinoma.

Mouse (Murine) PR Domain Containing 2, with ZNF Domain (PRDM2) interaction partners

  1. RIZ1 is an important regulator of both Akt3 (show AKT3 Proteins) transcription and AKT (show AKT1 Proteins) phosphorylation and suggest a role for RIZ1 in HF-induced obesity and the AKT (show AKT1 Proteins) pathway

  2. RIZ1 might participate osteoclast formation through the regulation of NFATc1 (show NFATC1 Proteins) expression.

  3. Data suggest that the histone methyltransferase RIZ1 is required for estrogen response in female reproductive tissues and that estrogen-bound estrogen receptors may turn a transcriptional repressor into a coactivator.

PRDM2 Protein Profile

Protein Summary

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PRDM2

  • PR domain containing 2, with ZNF domain (prdm2)
  • PR domain containing 2, with ZNF domain b (prdm2b)
  • PR domain containing 2, with ZNF domain (PRDM2)
  • similar to zinc finger protein RIZ (PRDM2)
  • PR domain containing 2, with ZNF domain (Prdm2)
  • 4833427P12Rik protein
  • E330024L24Rik protein
  • Gm1033 protein
  • Gm19732 protein
  • HUMHOXY1 protein
  • KMT8 protein
  • MGC114763 protein
  • MTB-ZF protein
  • PRDM2 protein
  • Riz protein
  • Riz1 protein
  • RIZ2 protein
  • Znfpr1c1 protein

Protein level used designations for PRDM2

PR domain containing 2, with ZNF domain , retinoblastoma protein-binding zinc finger protein-like , PR domain zinc finger protein 2-like , GATA-3 binding protein G3B , GATA-3-binding protein G3B , MTE-binding protein , PR domain zinc finger protein 2 , PR domain-containing protein 2 , lysine N-methyltransferase 8 , retinoblastoma protein-binding zinc finger protein , retinoblastoma protein-interacting zinc finger protein , zinc finger protein RIZ , zinc-finger DNA-binding protein , retinoblastoma interacting zinc finger protein

GENE ID SPECIES
494709 Xenopus laevis
797296 Danio rerio
100170624 Xenopus (Silurana) tropicalis
100350859 Oryctolagus cuniculus
100385110 Callithrix jacchus
100436958 Pongo abelii
100010516 Monodelphis domestica
469125 Pan troglodytes
100481446 Ailuropoda melanoleuca
100582767 Nomascus leucogenys
7799 Homo sapiens
110593 Mus musculus
313678 Rattus norvegicus
419478 Gallus gallus
100688431 Canis lupus familiaris
789222 Bos taurus
Selected quality suppliers for PRDM2 Proteins (PRDM2)
Did you look for something else?