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anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) Antibodies

The protein encoded by TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Additionally we are shipping Transient Receptor Potential Cation Channel, Subfamily M, Member 2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRPM2 7226 O94759
TRPM2 28240  
TRPM2 294329  
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Top anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 2 Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-TRPM2 antibody, IHC(P) IHC(P): Rat Brain Tissue Anti-TRPM2 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate ... 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Heart, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Goat Un-conjugated IHC (p) Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC (p) Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse probed with Rabbit Anti-TRPM2 Polyclonal Antibody, Unconjugated ... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB TRPM2 antibody was used for immunohistochemistry at a concentration of... Western Blot showing TRPM2 antibody used at a concentration of 1 ug/ml... 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Mouse Rabbit Un-conjugated ICC, ELISA   25 μg Log in to see 9 to 11 Days
$683.00
Details

TRPM2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 2 Antibodies

  1. Cow (Bovine) Polyclonal TRPM2 Primary Antibody for IHC, WB - ABIN2781840 : Hecquet, Ahmmed, Vogel, Malik: Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability. in Circulation research 2008 (PubMed)

  2. Mouse (Murine) Polyclonal TRPM2 Primary Antibody for ICC, ELISA - ABIN361530 : Kaneko, Kawakami, Hara, Wakamori, Itoh, Minami, Takada, Kume, Katsuki, Mori, Akaike: A critical role of TRPM2 in neuronal cell death by hydrogen peroxide. in Journal of pharmacological sciences 2006 (PubMed)

More Antibodies against Transient Receptor Potential Cation Channel, Subfamily M, Member 2 Interaction Partners

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) interaction partners

  1. Study determined the sequence of pig TRPC1 and TRPC3-7 channels and found pig TRPC cDNAs resemble their human homologs more than the others .

  2. heteromeric cation channels comprised of the TRPP2 mutant and the TRPC3 (show TRPC3 Antibodies) or TRPC7 protein induce enhanced receptor-activated Ca(2 (show CA2 Antibodies)+) influx that may lead to dysregulated cell growth in ADPKD

Human Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) interaction partners

  1. This is expected to provide a basis for inhibiting TRPM2 (show CLU Antibodies) for the improved treatment of breast cancer, which potentially includes treating breast tumors that are resistant to chemotherapy due to their evasion of apoptosis.

  2. In a transgenic mouse model of Alzheimer's disease, TRPM2 (show CLU Antibodies) was involved in neuronal toxicity and memory impairment.

  3. These findings shed new light on the evolution of TRPM2 (show CLU Antibodies) and establish nvTRPM2 as a promising tool to decipher its complex gating mechanisms.

  4. we report here a novel effect promoted by TRPM2 (show CLU Antibodies), where it functions to minimize DNA damage and thus may have a role in the protection of genomic DNA in breast cancer cells.

  5. The HDACi-elicited upregulation of TRPM2 (show CLU Antibodies) expression.

  6. TRPM2 (show CLU Antibodies) actively regulates the phosphorylation of GSK-3 (show GSK3b Antibodies) in the brain.

  7. The degradation of zonula occludens-1 (ZO-1 (show TJP1 Antibodies)), and claudin-2 (show CLDN2 Antibodies) exhibited a great dependence on the activation of the transient receptor potential melastatin (show TRPM1 Antibodies) (TRPM) 2 (show CLU Antibodies) channel, phospholipase Cgamma1 (PLCgamma1 (show PLCG1 Antibodies)) and the protein kinase (show CDK7 Antibodies) Calpha (show PRKACA Antibodies) (PKCalpha (show PKCa Antibodies)) signaling cascade.

  8. Although further analyses are needed to clarify the mechanism underlying TRPM2 (show CLU Antibodies)-mediated insulin (show INS Antibodies) secretion, TRPM2 (show CLU Antibodies) could be a key player in the regulation of insulin (show INS Antibodies) secretion and could represent a new target for diabetes therapy

  9. TRPM2 (show CLU Antibodies)-AS knockdown led to prostate cancer apoptosis, with a transcriptional profile indicating an increase in cellular stress, which was coupled to cell cycle arrest, an increase in intracellular hydrogen peroxide and activation of the sense TRPM2 (show CLU Antibodies) gene.

  10. VEGF-induced angiogenesis required reactive oxygen species generation in endothelial cells and resultant TRPM2 activation.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) interaction partners

  1. findings provide compelling evidence that F. tularensis catalase (show CAT Antibodies) restricts reactive oxygen species to temper macrophage TRPM2-mediated Ca(2 (show CA2 Antibodies)+) signaling and limit host immune function.

  2. TRPM2 plays roles in a wide range of pathological pain models based on peripheral and central neuroinflammation, rather than physiological nociceptive pain.

  3. The findings provide evidence for a mechanism by which Abeta (show APP Antibodies) impairs neurovascular regulation and suggest that TRPM2 channels are a potential therapeutic target to counteract cerebrovascular dysfunction in Alzheimer's dementia.

  4. Neointimal hyperplasia was substantially reduced in Trpm2 knockout mice.

  5. endogenous redox signals in pancreatic beta cells elevate insulin (show INS Antibodies) secretion via TRPM2 sensitization and activity at body temperature

  6. These results provide the first evidence to show a critical role for TRPM2 channel activation during reperfusion in the delayed increase in the [Zn(2+)]c and CA1 (show CA1 Antibodies) pyramidal neuronal death.

  7. Postischemic neovascularization in mice required reactive oxygen species generation in endothelial cells and resultant TRPM2 activation.

  8. neurons from the brain of Trpm2-deficient mice have significantly longer neurites with a greater number of spines.

  9. Ca2 (show CA2 Antibodies)+ entry via Trpm2 channels was essential for maintenance of mitochondrial function in the heart.

  10. TNF-alpha (show TNF Antibodies) induces a TRPM2 current in adult ventricular cardiomyocytes.

Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) Antigen Profile

Protein Summary

The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Gene names and symbols associated with TRPM2

  • transient receptor potential cation channel, subfamily M, member 2 (TRPM2) antibody
  • transient receptor potential cation channel, subfamily M, member 2 (trpm2) antibody
  • transient receptor potential cation channel, subfamily M, member 2 (Trpm2) antibody
  • 9830168K16Rik antibody
  • C79133 antibody
  • EREG1 antibody
  • KNP3 antibody
  • LTRPC2 antibody
  • NUDT9H antibody
  • NUDT9L1 antibody
  • si:ch73-263b18.1 antibody
  • Trp7 antibody
  • TRPC7 antibody
  • TRPM2 antibody
  • Trpm2-predicted antibody
  • Trrp7 antibody

Protein level used designations for TRPM2

transient receptor potential cation channel, subfamily M, member 2 , transient receptor potential cation channel, subfamily C, member 7 , transient receptor potential cation channel, subfamily C, member 7-like , short transient receptor potential channel 7-like , transient receptor potential cation channel subfamily M member 2-like , transient receptor potential channel subfamily C member 7 , LTrpC-2 , estrogen-responsive element-associated gene 1 protein , long transient receptor potential channel 2 , transient receptor potential cation channel subfamily M member 2 , transient receptor potential channel 7 , transient receptor protein 7 , transient receptor potential melastatin family 2

GENE ID SPECIES
424835 Gallus gallus
470101 Pan troglodytes
703611 Macaca mulatta
799412 Danio rerio
100056810 Equus caballus
100083361 Ornithorhynchus anatinus
100124999 Xenopus (Silurana) tropicalis
100341596 Oryctolagus cuniculus
100443123 Pongo abelii
100479298 Ailuropoda melanoleuca
100479364 Ailuropoda melanoleuca
100539776 Meleagris gallopavo
100556895 Anolis carolinensis
100271727 Sus scrofa
7226 Homo sapiens
28240 Mus musculus
294329 Rattus norvegicus
508029 Bos taurus
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